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P71348 (ALAA_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate-pyruvate aminotransferase AlaA

EC=2.6.1.2
Gene names
Name:alaA
Ordered Locus Names:HI_0286
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of alanine By similarity.

Catalytic activity

L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 404404Glutamate-pyruvate aminotransferase AlaA
PRO_0000123869

Sites

Binding site411Substrate; via amide nitrogen By similarity
Binding site1791Substrate By similarity
Binding site3781Substrate By similarity

Amino acid modifications

Modified residue2401N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
P71348 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 7F2C3E24CC69FB46

FASTA40445,160
        10         20         30         40         50         60 
MRLFPKSDKL EHVCYDIRGP VHKEALRLEE EGNKILKLNI GNPAPFGFEA PDEILVDVLR 

        70         80         90        100        110        120 
NLPSAQGYCD SKGLYSARKA IVQYYQSKGI LGATVNDVYI GNGVSELITM AMQALLNDGD 

       130        140        150        160        170        180 
EVLVPMPDYP LWTAAVTLSG GKAVHYLCDE DANWFPTIDD IKAKVNAKTK AIVIINPNNP 

       190        200        210        220        230        240 
TGAVYSKELL QEIVEIARQN NLIIFADEIY DKILYDGAVH HHIAALAPDL LTVTLNGLSK 

       250        260        270        280        290        300 
AYRVAGFRQG WMILNGPKHN AKGYIEGLDM LASMRLCANV PMQHAIQTAL GGYQSINEFI 

       310        320        330        340        350        360 
LPGGRLLEQR NKAYDLITQI PGITCVKPMG AMYMFPKIDV KKFNIHSDEK MVLDLLRQEK 

       370        380        390        400 
VLLVHGKGFN WHSPDHFRIV TLPYVNQLEE AITKLARFLS DYRQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC21948.1.
RefSeqNP_438453.1. NC_000907.1.

3D structure databases

ProteinModelPortalP71348.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0286.

Proteomic databases

PRIDEP71348.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21948; AAC21948; HI_0286.
GeneID949411.
KEGGhin:HI0286.
PATRIC20189111. VBIHaeInf48452_0302.

Phylogenomic databases

eggNOGCOG0436.
KOK14260.
OMARIVFLPH.
OrthoDBEOG6X9MJ6.
ProtClustDBPRK09265.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALAA_HAEIN
AccessionPrimary (citable) accession number: P71348
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: February 1, 1997
Last modified: February 19, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names