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P71342

- NQRE_HAEIN

UniProt

P71342 - NQRE_HAEIN

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Protein
Na(+)-translocating NADH-quinone reductase subunit E
Gene
nqrE, HI_0170
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.UniRule annotation

Catalytic activityi

NADH + ubiquinone + Na+(In) = NAD+ + ubiquinol + Na+(Out).UniRule annotation

GO - Molecular functioni

  1. oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor Source: UniProtKB-HAMAP

GO - Biological processi

  1. respiratory electron transport chain Source: InterPro
  2. sodium ion transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

NAD, Sodium, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
Na(+)-translocating NADH-quinone reductase subunit E (EC:1.6.5.-)
Short name:
Na(+)-NQR subunit E
Short name:
Na(+)-translocating NQR subunit E
Alternative name(s):
NQR complex subunit E
NQR-1 subunit E
Gene namesi
Name:nqrE
Ordered Locus Names:HI_0170
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei11 – 3121Helical; Reviewed prediction
Add
BLAST
Transmembranei35 – 5521Helical; Reviewed prediction
Add
BLAST
Transmembranei77 – 9721Helical; Reviewed prediction
Add
BLAST
Transmembranei110 – 13021Helical; Reviewed prediction
Add
BLAST
Transmembranei140 – 16021Helical; Reviewed prediction
Add
BLAST
Transmembranei176 – 19621Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. Gram-negative-bacterium-type cell wall Source: InterPro
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Na(+)-translocating NADH-quinone reductase subunit EUniRule annotation
PRO_0000214252Add
BLAST

Interactioni

Subunit structurei

Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF By similarity.

Protein-protein interaction databases

STRINGi71421.HI0170.

Family & Domainsi

Sequence similaritiesi

Belongs to the NqrDE/RnfAE family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2209.
KOiK00350.
OMAiKIRYSNV.
OrthoDBiEOG6GBMG7.
PhylomeDBiP71342.

Family and domain databases

HAMAPiMF_00429. NqrE.
InterProiIPR003667. Elect_transpt_cplx_Rnf/Nqr.
IPR010967. NADH_UbQ_OxRdtase_suE.
[Graphical view]
PfamiPF02508. Rnf-Nqr. 1 hit.
[Graphical view]
PIRSFiPIRSF006102. NQR_DE. 1 hit.
TIGRFAMsiTIGR01940. nqrE. 1 hit.

Sequencei

Sequence statusi: Complete.

P71342-1 [UniParc]FASTAAdd to Basket

« Hide

MEHYISLFVK AVFIENMALS FFLGMCTFLA VSKKVSPAFG LGIAVTFVLG    50
IAVPVNQLIY ANVLKENALI EGVDLSFLNF ITFIGVIAGL VQILEMVLDK 100
FMPSLYNALG IFLPLIAVNC AIFGGVSFMV QRDYNFPESI VYGFGSGLGW 150
MLAIVALAGL TEKMKYADIP AGLKGLGITF ISVGLMALGF MSFSGIQL 198
Length:198
Mass (Da):21,306
Last modified:February 1, 1997 - v1
Checksum:i29C6544D4BF71BDE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC21840.1.
RefSeqiNP_438338.1. NC_000907.1.
WP_010868950.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC21840; AAC21840; HI_0170.
GeneIDi951077.
KEGGihin:HI0170.
PATRICi20188835. VBIHaeInf48452_0174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC21840.1 .
RefSeqi NP_438338.1. NC_000907.1.
WP_010868950.1. NC_000907.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0170.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC21840 ; AAC21840 ; HI_0170 .
GeneIDi 951077.
KEGGi hin:HI0170.
PATRICi 20188835. VBIHaeInf48452_0174.

Phylogenomic databases

eggNOGi COG2209.
KOi K00350.
OMAi KIRYSNV.
OrthoDBi EOG6GBMG7.
PhylomeDBi P71342.

Family and domain databases

HAMAPi MF_00429. NqrE.
InterProi IPR003667. Elect_transpt_cplx_Rnf/Nqr.
IPR010967. NADH_UbQ_OxRdtase_suE.
[Graphical view ]
Pfami PF02508. Rnf-Nqr. 1 hit.
[Graphical view ]
PIRSFi PIRSF006102. NQR_DE. 1 hit.
TIGRFAMsi TIGR01940. nqrE. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
  2. "Existence of Na+-translocating NADH-quinone reductase in Haemophilus influenzae."
    Hayashi M., Nakayama Y., Unemoto T.
    FEBS Lett. 381:174-176(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION AS NQR SYSTEM.
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiNQRE_HAEIN
AccessioniPrimary (citable) accession number: P71342
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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