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Protein

Colanic acid biosynthesis protein WcaM

Gene

wcaM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Biological processi

Keywordsi

Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7094-MONOMER
UniPathwayiUPA00936

Names & Taxonomyi

Protein namesi
Recommended name:
Colanic acid biosynthesis protein WcaM
Gene namesi
Name:wcaM
Synonyms:yefK
Ordered Locus Names:b2043, JW2028
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12651 wcaM

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Tat-type signalSequence analysisAdd BLAST28
ChainiPRO_000006595829 – 464Colanic acid biosynthesis protein WcaMAdd BLAST436

Post-translational modificationi

Exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Proteomic databases

PaxDbiP71244
PRIDEiP71244

Interactioni

Protein-protein interaction databases

BioGridi4259677, 196 interactors
IntActiP71244, 4 interactors
STRINGi316385.ECDH10B_2193

Structurei

3D structure databases

ProteinModelPortaliP71244
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105G1A Bacteria
ENOG4110WUJ LUCA
HOGENOMiHOG000121919
KOiK16711
OMAiVRGKFMA

Family and domain databases

InterProiView protein in InterPro
IPR023882 Colanic_acid_synth_WcaM
IPR011050 Pectin_lyase_fold/virulence
SUPFAMiSSF51126 SSF51126, 1 hit
TIGRFAMsiTIGR04004 WcaM, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P71244-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFKKLSRRT FLTASSALAF LHTPFARALP ARQSVNINDY NPHDWIASFK
60 70 80 90 100
QAFSEGQTVV VPAGLVCDNI NTGIFIPPGK TLHILGSLRG NGRGRFVLQD
110 120 130 140 150
GSQVTGEDGG SMHNITLDVR GSDCTIKGLT MSGFGPVTQI YIGGKNKRVM
160 170 180 190 200
RNLIIDNLTV SHANYAILRQ GFHNQIIGAN ITNCKFSDLQ GDAIEWNVAI
210 220 230 240 250
NDRDILISDH VIERINCTNG KINWGIGIGL AGSTYDNNYP EDQAVKNFVV
260 270 280 290 300
ANITGSDCRQ LIHVENGKHF VIRNIKARNI TPDFSKKAGI DNATVAIYGC
310 320 330 340 350
DNFVIDNIEM INSAGMLIGY GVIKGKYLSI PQNFRVNDIQ LDNTHLAYKL
360 370 380 390 400
RGIQISAGNA VSFVALTNIE MKRASLELHN KPQHFFMRNI NVMQESSVGP
410 420 430 440 450
ALSMNFDMRK DVRGVFMAKK ETLLSLANVH AVNEKGQSSV DIDRINHHIV
460
NVEKINFRLP ELRE
Length:464
Mass (Da):51,316
Last modified:November 1, 1997 - v2
Checksum:i72A7655DC07368BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA Translation: AAC77852.1
U00096 Genomic DNA Translation: AAC75104.1
AP009048 Genomic DNA Translation: BAA15897.1
PIRiB64970
RefSeqiNP_416547.1, NC_000913.3
WP_001116026.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75104; AAC75104; b2043
BAA15897; BAA15897; BAA15897
GeneIDi946561
KEGGiecj:JW2028
eco:b2043
PATRICifig|1411691.4.peg.208

Similar proteinsi

Entry informationi

Entry nameiWCAM_ECOLI
AccessioniPrimary (citable) accession number: P71244
Secondary accession number(s): P76378
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health