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Protein

Putative colanic acid biosynthesis glycosyltransferase WcaL

Gene

wcaL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7095-MONOMER
UniPathwayiUPA00936

Protein family/group databases

CAZyiGT4 Glycosyltransferase Family 4

Names & Taxonomyi

Protein namesi
Recommended name:
Putative colanic acid biosynthesis glycosyltransferase WcaL (EC:2.4.-.-)
Gene namesi
Name:wcaL
Synonyms:yefL
Ordered Locus Names:b2044, JW2029
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12652 wcaL

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000803111 – 406Putative colanic acid biosynthesis glycosyltransferase WcaLAdd BLAST406

Proteomic databases

PaxDbiP71243
PRIDEiP71243

Interactioni

Protein-protein interaction databases

BioGridi4259676, 168 interactors
DIPiDIP-11127N
IntActiP71243, 1 interactor
STRINGi316385.ECDH10B_2194

Structurei

3D structure databases

ProteinModelPortaliP71243
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107T8Q Bacteria
COG0438 LUCA
HOGENOMiHOG000121940
InParanoidiP71243
KOiK16703
OMAiRYPRYSE
PhylomeDBiP71243

Family and domain databases

InterProiView protein in InterPro
IPR023884 Colanic_acid_synth_WcaL
IPR001296 Glyco_trans_1
IPR028098 Glyco_trans_4-like_N
PfamiView protein in Pfam
PF13439 Glyco_transf_4, 1 hit
PF00534 Glycos_transf_1, 1 hit
TIGRFAMsiTIGR04005 wcaL, 1 hit

Sequencei

Sequence statusi: Complete.

P71243-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVGFFLLKF PLSSETFVLN QITAFIDMGF EVEILALQKG DTQNTHAAWT
60 70 80 90 100
KYNLAARTRW LQDEPTGKVA KLRHRASQTL RGIHRKNTWQ ALNLKRYGAE
110 120 130 140 150
SRNLILSAIC GQVATPFRAD VFIAHFGPAG VTAAKLRELG VIRGKIATIF
160 170 180 190 200
HGIDISSREV LNHYTPEYQQ LFRRGDLMLP ISDLWAGRLQ KMGCPREKIA
210 220 230 240 250
VSRMGVDMTR FSPRPVKAPA TPLEIISVAR LTEKKGLHVA IEACRQLKEQ
260 270 280 290 300
GVAFRYRILG IGPWERRLRT LIEQYQLEDV VEMPGFKPSH EVKAMLDDAD
310 320 330 340 350
VFLLPSVTGA DGDMEGIPVA LMEAMAVGIP VVSTLHSGIP ELVEADKSGW
360 370 380 390 400
LVPENDARAL AQRLAAFSQL DTDELAPVVK RAREKVEHDF NQQVINRELA

SLLQAL
Length:406
Mass (Da):45,362
Last modified:November 1, 1997 - v2
Checksum:iEBC64DB398677D65
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti126F → Y in AAC77851 (Ref. 2) Curated1
Sequence conflicti129A → T in AAC77851 (Ref. 2) Curated1
Sequence conflicti144G → A in AAC77851 (Ref. 2) Curated1
Sequence conflicti205G → A in AAC77851 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA Translation: AAC77851.1
U00096 Genomic DNA Translation: AAC75105.1
AP009048 Genomic DNA Translation: BAA15898.1
PIRiC64970
RefSeqiNP_416548.1, NC_000913.3
WP_000862592.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75105; AAC75105; b2044
BAA15898; BAA15898; BAA15898
GeneIDi946565
KEGGiecj:JW2029
eco:b2044
PATRICifig|1411691.4.peg.207

Entry informationi

Entry nameiWCAL_ECOLI
AccessioniPrimary (citable) accession number: P71243
Secondary accession number(s): P76379
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 25, 2018
This is version 117 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health