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Protein

Putative colanic acid polymerase

Gene

wcaD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Biological processi

Keywordsi

Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7101-MONOMER
UniPathwayiUPA00936

Names & Taxonomyi

Protein namesi
Recommended name:
Putative colanic acid polymerase
Gene namesi
Name:wcaD
Ordered Locus Names:b2056, JW2041
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13572 wcaD

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Transmembranei27 – 47HelicalSequence analysisAdd BLAST21
Transmembranei55 – 75HelicalSequence analysisAdd BLAST21
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei204 – 224HelicalSequence analysisAdd BLAST21
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Transmembranei327 – 347HelicalSequence analysisAdd BLAST21
Transmembranei376 – 396HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000659551 – 405Putative colanic acid polymeraseAdd BLAST405

Proteomic databases

PaxDbiP71238
PRIDEiP71238

Interactioni

Protein-protein interaction databases

BioGridi4259688, 157 interactors
DIPiDIP-11120N
IntActiP71238, 1 interactor
STRINGi316385.ECDH10B_2206

Structurei

3D structure databases

ProteinModelPortaliP71238
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108NYJ Bacteria
ENOG410ZIK0 LUCA
HOGENOMiHOG000267975
KOiK13620
OMAiWRSMSTS

Family and domain databases

InterProiView protein in InterPro
IPR024013 Colanic_acid_synth_WcaD
TIGRFAMsiTIGR04010 WcaD, 1 hit

Sequencei

Sequence statusi: Complete.

P71238-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTSIRICSY LLLPLIYLLV NVKIAQLGES FPITIVTFLP VLLLLFLERI
60 70 80 90 100
SVKKLMIALG IGAGLTAFNY LFGQSLDASK YVTSTMLFVY IVIIIGMVWS
110 120 130 140 150
IRFKTISPHN HRKILRFFYL VVGLVVALAA VEMAQIILTG GSSIMESISK
160 170 180 190 200
YLIYSNSYVL NFIKFGGKRT TALYFEPAFF ALALISIWLS IKQFGIKTPK
210 220 230 240 250
TDAMILAGII LSGSFSGVMT FILFYLLEWA FQYLNKEAIK KKLPLALISL
260 270 280 290 300
AVFLVGVVIA FPYISTRLGD LGTEGSSSYY RIVGPLVMVG YSLTHIDGVV
310 320 330 340 350
RFGSLYEYVA SFGIFNGADV GKTIDNGLYL LIIYFSWFAV FLSLWYMGKV
360 370 380 390 400
IKMMINAFGD NRNFRVQLYL FTPVSLFFTG SIFSPEYAFL IVCPFILRKA

LNITR
Length:405
Mass (Da):45,409
Last modified:November 1, 1997 - v2
Checksum:iA3D9D91255686043
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti108P → A in AAC77839 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA Translation: AAC77839.1
U00096 Genomic DNA Translation: AAC75117.1
AP009048 Genomic DNA Translation: BAE76573.1
PIRiG64971
RefSeqiNP_416560.1, NC_000913.3
WP_000107816.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75117; AAC75117; b2056
BAE76573; BAE76573; BAE76573
GeneIDi946550
KEGGiecj:JW2041
eco:b2056
PATRICifig|511145.12.peg.2133

Similar proteinsi

Entry informationi

Entry nameiWCAD_ECOLI
AccessioniPrimary (citable) accession number: P71238
Secondary accession number(s): P76385, Q2MAY3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

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