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Protein

Putative colanic acid biosynthesis glycosyl transferase WcaC

Gene

wcaC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7102-MONOMER.
ECOL316407:JW2042-MONOMER.
UniPathwayiUPA00936.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative colanic acid biosynthesis glycosyl transferase WcaC
Gene namesi
Name:wcaC
Ordered Locus Names:b2057, JW2042
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13571. wcaC.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Putative colanic acid biosynthesis glycosyl transferase WcaCPRO_0000065954Add
BLAST

Proteomic databases

PaxDbiP71237.
PRIDEiP71237.

Interactioni

Protein-protein interaction databases

BioGridi4260675. 294 interactions.
DIPiDIP-11119N.
IntActiP71237. 6 interactions.
MINTiMINT-1255947.
STRINGi511145.b2057.

Structurei

3D structure databases

ProteinModelPortaliP71237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4107RXY. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000121966.
InParanoidiP71237.
KOiK13684.
OMAiVKVDRAH.
OrthoDBiEOG6F296H.
PhylomeDBiP71237.

Family and domain databases

InterProiIPR023916. Colanic_acid_synth_WcaC.
IPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4-like_N.
[Graphical view]
PfamiPF13439. Glyco_transf_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04015. WcaC. 1 hit.

Sequencei

Sequence statusi: Complete.

P71237-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNILQFNVRL AEGGAAGVAL DLHQRALQQG LASHFVYGYG KGGKESVSHQ
60 70 80 90 100
NYPQVIKHTP RMTAMANIAL FRLFNRDLFG NFNELYRTIT RTAGPVVLHF
110 120 130 140 150
HVLHSYWLNL KSVVRFCEKV KNHKPDVTLV WTLHDHWSVT GRCAFTDGCE
160 170 180 190 200
GWKTGCQKCP TLNNYPPVKI DRAHQLVAGK RQLFREMLAL GCQFISPSQH
210 220 230 240 250
VADAFNSLYG PGRCRIINNG IDMATEAILA DLPPVRETQG KPKIAVVAHD
260 270 280 290 300
LRYDGKTNQQ LVREMMALGD KIELHTFGKF SPFTAGNVVN HGFETDKRKL
310 320 330 340 350
MSALNQMDAL VFSSRVDNYP LILCEALSIG VPVIATHSDA AREVLQKSGG
360 370 380 390 400
KTVSEEEVLQ LVQLSKPEIA QAIFGTTLAE FSQRSRAAYS GQQMLEEYVN

FYQNL
Length:405
Mass (Da):45,260
Last modified:November 1, 1997 - v2
Checksum:i9A321E69131E3665
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti232 – 2321L → F in AAC77838 (Ref. 2) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77838.1.
U00096 Genomic DNA. Translation: AAC75118.1.
AP009048 Genomic DNA. Translation: BAE76574.1.
PIRiH64971.
RefSeqiNP_416561.1. NC_000913.3.
WP_001023871.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75118; AAC75118; b2057.
BAE76574; BAE76574; BAE76574.
GeneIDi946579.
KEGGiecj:JW2042.
eco:b2057.
PATRICi32119447. VBIEscCol129921_2134.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77838.1.
U00096 Genomic DNA. Translation: AAC75118.1.
AP009048 Genomic DNA. Translation: BAE76574.1.
PIRiH64971.
RefSeqiNP_416561.1. NC_000913.3.
WP_001023871.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP71237.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260675. 294 interactions.
DIPiDIP-11119N.
IntActiP71237. 6 interactions.
MINTiMINT-1255947.
STRINGi511145.b2057.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Proteomic databases

PaxDbiP71237.
PRIDEiP71237.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75118; AAC75118; b2057.
BAE76574; BAE76574; BAE76574.
GeneIDi946579.
KEGGiecj:JW2042.
eco:b2057.
PATRICi32119447. VBIEscCol129921_2134.

Organism-specific databases

EchoBASEiEB3341.
EcoGeneiEG13571. wcaC.

Phylogenomic databases

eggNOGiENOG4107RXY. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000121966.
InParanoidiP71237.
KOiK13684.
OMAiVKVDRAH.
OrthoDBiEOG6F296H.
PhylomeDBiP71237.

Enzyme and pathway databases

UniPathwayiUPA00936.
BioCyciEcoCyc:G7102-MONOMER.
ECOL316407:JW2042-MONOMER.

Miscellaneous databases

PROiP71237.

Family and domain databases

InterProiIPR023916. Colanic_acid_synth_WcaC.
IPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4-like_N.
[Graphical view]
PfamiPF13439. Glyco_transf_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04015. WcaC. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid."
    Stevenson G., Andrianopoulos K., Hobbs M., Reeves P.R.
    J. Bacteriol. 178:4885-4893(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Reeves P.R.
    Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION TO 9-54.
    Strain: K12.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiWCAC_ECOLI
AccessioniPrimary (citable) accession number: P71237
Secondary accession number(s): P76386, Q2MAY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 11, 2016
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.