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P71103 (PTAS_CLOAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:CA_C1742
OrganismClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) [Reference proteome] [HAMAP]
Taxonomic identifier272562 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetate biosynthetic process

Inferred from direct assay Ref.1. Source: MENGO

acetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 333333Phosphate acetyltransferase
PRO_0000179125

Experimental info

Sequence conflict2151S → G in AAB18300. Ref.1
Sequence conflict2371D → H in AAB18300. Ref.1
Sequence conflict3121G → S in AAB18300. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P71103 [UniParc].

Last modified August 29, 2001. Version 2.
Checksum: EDB3FDE702BECC2D

FASTA33336,140
        10         20         30         40         50         60 
MDLIESIWEC AKQDKKRIIL AEGEEKRNLI AADKIIKEGL AELVLVGDEN KIKEKASELN 

        70         80         90        100        110        120 
LDISKAEIMD PETSLKTETY ARDFYELRKH KGMTIEKSEK MVRDPLYFAT MALKDGYVDG 

       130        140        150        160        170        180 
MVSGAVHTTG DLLRPGLQII KTAPGVKIVS GFFVMIIPDC DYGEEGLLLF ADCAVNPNPT 

       190        200        210        220        230        240 
SDELADIAIT TAETARKLCN VEPKVAMLSF STMGSAKGEM VDKVKNAVEI TKKFRPDLAI 

       250        260        270        280        290        300 
DGELQLDAAI DSEVAALKAP SSNVAGNANV LVFPDLQTGN IGYKLVQRFA KAKAIGPICQ 

       310        320        330 
GFAKPINDLS RGCSSEDIVN VVAITVVQAQ RGI 

« Hide

References

« Hide 'large scale' references
[1]"Cloning, sequencing, and expression of genes encoding phosphotransacetylase and acetate kinase from Clostridium acetobutylicum ATCC 824."
Boynton Z.L., Bennett G.N., Rudolph F.B.
Appl. Environ. Microbiol. 62:2758-2766(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.
[2]"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum."
Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R.
J. Bacteriol. 183:4823-4838(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U38234 Genomic DNA. Translation: AAB18300.1.
AE001437 Genomic DNA. Translation: AAK79708.1.
PIRA97115.
RefSeqNP_348368.1. NC_003030.1.

3D structure databases

ProteinModelPortalP71103.
SMRP71103. Positions 1-331.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272562.CA_C1742.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK79708; AAK79708; CA_C1742.
GeneID1117925.
KEGGcac:CA_C1742.
PATRIC32037862. VBICloAce74127_1944.

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053796.
KOK00625.
OMACEYGENG.
OrthoDBEOG6BKJ5W.

Enzyme and pathway databases

BioCycCACE272562:GJIH-1791-MONOMER.
MetaCyc:PTACLOS-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

InterProIPR012147. P_Ac_Bu_trans.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTAS_CLOAB
AccessionPrimary (citable) accession number: P71103
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 29, 2001
Last modified: May 14, 2014
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways