P71103 (PTAS_CLOAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	CA_C1742

Organism

Clostridium acetobutylicum

Taxonomic identifier

1488 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 333	333	Phosphate acetyltransferase		PRO_0000179125
Experimental info
	Sequence conflict	215	1	S → G in AAB18300. Ref.1
	Sequence conflict	237	1	D → H in AAB18300. Ref.1
	Sequence conflict	312	1	G → S in AAB18300. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P71103 [UniParc]. Last modified August 29, 2001. Version 2. Checksum: EDB3FDE702BECC2D	FASTA	333	36,140
	10 20 30 40 50 60 MDLIESIWEC AKQDKKRIIL AEGEEKRNLI AADKIIKEGL AELVLVGDEN KIKEKASELN 70 80 90 100 110 120 LDISKAEIMD PETSLKTETY ARDFYELRKH KGMTIEKSEK MVRDPLYFAT MALKDGYVDG 130 140 150 160 170 180 MVSGAVHTTG DLLRPGLQII KTAPGVKIVS GFFVMIIPDC DYGEEGLLLF ADCAVNPNPT 190 200 210 220 230 240 SDELADIAIT TAETARKLCN VEPKVAMLSF STMGSAKGEM VDKVKNAVEI TKKFRPDLAI 250 260 270 280 290 300 DGELQLDAAI DSEVAALKAP SSNVAGNANV LVFPDLQTGN IGYKLVQRFA KAKAIGPICQ 310 320 330 GFAKPINDLS RGCSSEDIVN VVAITVVQAQ RGI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, sequencing, and expression of genes encoding phosphotransacetylase and acetate kinase from Clostridium acetobutylicum ATCC 824." Boynton Z.L., Bennett G.N., Rudolph F.B. Appl. Environ. Microbiol. 62:2758-2766(1996) [PubMed: 8702268] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.
[2]	"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U38234 Genomic DNA. Translation: AAB18300.1. AE001437 Genomic DNA. Translation: AAK79708.1.
PIR	A97115.
RefSeq	NP_348368.1. NC_003030.1.
3D structure databases
ProteinModelPortal	P71103.
SMR	P71103. Positions 1-331.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1117925.
GenomeReviews	Gene locus CA_C1742 in contig AE001437_GR.
KEGG	cac:CA_C1742.
NMPDR	fig|272562.1.peg.1897.
PATRIC	32037862. VBICloAce74127_1944.
Phylogenomic databases
HOGENOM	HBG576804.
OMA	LVFPDLQ.
PhylomeDB	P71103.
ProtClustDB	PRK09653.
Enzyme and pathway databases
BioCyc	CACE272562:CAC1742-MONOMER. MetaCyc:PTACLOS-MONOMER.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K00625.
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTAS_CLOAB

Accession

Primary (citable) accession number: P71103

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	August 29, 2001
Last modified:	January 25, 2012
This is version 76 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program