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Reviewed, UniProtKB/Swiss-Prot P71019 (FABD_BACSU)

Last modified November 3, 2009. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Malonyl CoA-acyl carrier protein transacylase
      Short name=MCT
    EC=2.3.1.39
Gene names
Name: fabD
Synonyms: ylpE
Ordered Locus Names: BSU15900
OrganismBacillus subtilis [Complete proteome] [HAMAP]
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-protein].

Pathway

Lipid metabolism; fatty acid biosynthesis.

Sequence similarities

Belongs to the fabD family.

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Ontologies

Keywords
   Biological processFatty acid biosynthesis
Lipid synthesis
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function[acyl-carrier-protein] S-malonyltransferase activity

Inferred from electronic annotation. Source: EC

binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 317317Malonyl CoA-acyl carrier protein transacylase
PRO_0000194210

Sites

Active site911 By similarity
Active site2011 By similarity

Experimental info

Sequence conflict124 – 1318VPAGEGAM → GCRLAKEQW Ref.1

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Sequences

Sequence LengthMass (Da)Tools
P71019-1 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: 191AE828B1C91D7F

FASTA31734,035
        10         20         30         40         50         60 
MSKIAFLFPG QGSQFIGMGK ELYEQVPAAK RLFDEADETL ETKLSSLIFE GDAEELTLTY 

        70         80         90        100        110        120 
NAQPALLTTS IAVLEKFKES GITPDFTAGH SLGEYSALVA AGALSFKDAV YTVRKRGEFM 

       130        140        150        160        170        180 
NEAVPAGEGA MAAILGMDAE ALKQVTDKVT EEGNLVQLAN LNCPGQIVIS GTAKGVELAS 

       190        200        210        220        230        240 
ELAKENGAKR AIPLEVSGPF HSELMKPAAE KLKEVLDACD IKDADVPVIS NVSADVMTEK 

       250        260        270        280        290        300 
ADIKEKLIEQ LYSPVRFEES INKLIAEGVT TFIEIGPGKV LSGLVKKVNR RLKTIAVSDP 

       310 
ETIELAIQTL KEENDNA

« Hide

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References

« Hide 'large scale' references
[1]"Bacillus subtilis acyl carrier protein is encoded in a cluster of lipid biosynthesis genes."
Morbidoni H.R., de Mendoza D., Cronan J.E. Jr.
J. Bacteriol. 178:4794-4800(1996) [PubMed: 8759840] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"A 28 kbp segment from the spoVM region of the Bacillus subtilis 168 genome."
Foulger D., Errington J.
Microbiology 144:801-805(1998) [PubMed: 9534248] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

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Cross-references

Sequence databases

U59433 Genomic DNA. Translation: AAC44306.1.
Y13937 Genomic DNA. Translation: CAA74249.1.
AL009126 Genomic DNA. Translation: CAB13463.1.
PIRH69620.
RefSeqNP_389472.1.

3D structure databases

HSSPHSSP built from PDB template 1MLA based on UniProtKB P25715.
ModBaseSearch...

Genome annotation databases

GeneID938488.
GenomeReviewsGene locus BSU15900 in contig AL009126_GR.
KEGGbsu:BSU15900.
NMPDRfig|224308.1.peg.1592.

Organism-specific databases

SubtiListBG11836. fabD. [Micado]
CMRSearch...

Phylogenomic databases

HOGENOMP71019.
OMACEIAKAK.

Enzyme and pathway databases

BioCycBSUB224308:BSU1591-MON.
BRENDA2.3.1.39. 150.

Family and domain databases

InterProIPR001227. Ac_transferase_reg.
IPR014043. Acyl_transferase.
IPR004410. FabD.
[Graphical view]
Gene3DG3DSA:3.40.366.10. Ac_transferase_reg. 1 hit.
PfamPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00128. fabD. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameFABD_BACSU
AccessionPrimary (citable) accession number: P71019
Secondary accession number(s): O34463
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: November 3, 2009
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents