Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P70999

- SPEB_BACSU

UniProt

P70999 - SPEB_BACSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Agmatinase

Gene

speB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalyzes the formation of putrescine from agmatine.

Catalytic activityi

Agmatine + H2O = putrescine + urea.

Cofactori

Mn2+PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi112 – 1121ManganesePROSITE-ProRule annotation
Metal bindingi135 – 1351ManganesePROSITE-ProRule annotation
Metal bindingi137 – 1371ManganesePROSITE-ProRule annotation
Metal bindingi139 – 1391ManganesePROSITE-ProRule annotation
Metal bindingi216 – 2161ManganesePROSITE-ProRule annotation
Metal bindingi218 – 2181ManganesePROSITE-ProRule annotation

GO - Molecular functioni

  1. agmatinase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. putrescine biosynthetic process from arginine Source: UniProtKB-UniPathway
  2. spermidine biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Polyamine biosynthesis, Putrescine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciBSUB:BSU37490-MONOMER.
MetaCyc:SPEBBACSU-MONOMER.
UniPathwayiUPA00534; UER00287.

Names & Taxonomyi

Protein namesi
Recommended name:
Agmatinase (EC:3.5.3.11)
Alternative name(s):
Agmatine ureohydrolase
Short name:
AUH
Gene namesi
Name:speB
Synonyms:ywhG
Ordered Locus Names:BSU37490
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570: Chromosome

Organism-specific databases

GenoListiBSU37490. [Micado]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 290290AgmatinasePRO_0000173728Add
BLAST

Proteomic databases

PaxDbiP70999.

Interactioni

Protein-protein interaction databases

STRINGi224308.BSU37490.

Structurei

3D structure databases

ProteinModelPortaliP70999.
SMRiP70999. Positions 18-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family. Agmatinase subfamily.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0010.
HOGENOMiHOG000204321.
InParanoidiP70999.
KOiK01480.
OMAiKPDYSLY.
OrthoDBiEOG6R2GW5.
PhylomeDBiP70999.

Family and domain databases

Gene3Di3.40.800.10. 1 hit.
InterProiIPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERiPTHR11358. PTHR11358. 1 hit.
PfamiPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFiPIRSF036979. Arginase. 1 hit.
TIGRFAMsiTIGR01230. agmatinase. 1 hit.
PROSITEiPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P70999-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRFDEAYSGK VFIASRPEWE EADAILYGMP MDWTVSYRPG SRFGPSRIRE
60 70 80 90 100
VSIGLEEYSP YLDRDLADLN FFDAGDIPLP FGNPQRSLDM IEEYVDSILE
110 120 130 140 150
KGKFPMGMGG EHLVSWPVIK AMYKKYPDLA IIHFDAHTDL RVDYEGEPLS
160 170 180 190 200
HSTPIRKAAE LIGPHNVYSF GIRSGMKEEF EWAKENGMHI SKFEVLEPLK
210 220 230 240 250
EVLPKLAGRP VYVTIDIDVL DPAHAPGTGT VDAGGITSKE LLASVHEIAR
260 270 280 290
SEVNVKGADL VEVAPVYDHS EQTANTASKI IREMLLGFVK
Length:290
Mass (Da):32,417
Last modified:February 1, 1997 - v1
Checksum:iB14C4AAD1B1BC964
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z80360 Genomic DNA. Translation: CAB02517.1.
AL009126 Genomic DNA. Translation: CAB15776.1.
PIRiH70057.
RefSeqiNP_391629.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB15776; CAB15776; BSU37490.
GeneIDi937205.
KEGGibsu:BSU37490.
PATRICi18979534. VBIBacSub10457_3929.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z80360 Genomic DNA. Translation: CAB02517.1 .
AL009126 Genomic DNA. Translation: CAB15776.1 .
PIRi H70057.
RefSeqi NP_391629.1. NC_000964.3.

3D structure databases

ProteinModelPortali P70999.
SMRi P70999. Positions 18-290.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224308.BSU37490.

Proteomic databases

PaxDbi P70999.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB15776 ; CAB15776 ; BSU37490 .
GeneIDi 937205.
KEGGi bsu:BSU37490.
PATRICi 18979534. VBIBacSub10457_3929.

Organism-specific databases

GenoListi BSU37490. [Micado ]

Phylogenomic databases

eggNOGi COG0010.
HOGENOMi HOG000204321.
InParanoidi P70999.
KOi K01480.
OMAi KPDYSLY.
OrthoDBi EOG6R2GW5.
PhylomeDBi P70999.

Enzyme and pathway databases

UniPathwayi UPA00534 ; UER00287 .
BioCyci BSUB:BSU37490-MONOMER.
MetaCyc:SPEBBACSU-MONOMER.

Family and domain databases

Gene3Di 3.40.800.10. 1 hit.
InterProi IPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view ]
PANTHERi PTHR11358. PTHR11358. 1 hit.
Pfami PF00491. Arginase. 1 hit.
[Graphical view ]
PIRSFi PIRSF036979. Arginase. 1 hit.
TIGRFAMsi TIGR01230. agmatinase. 1 hit.
PROSITEi PS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees)."
    Presecan E., Moszer I., Boursier L., Cruz Ramos H., De La Fuente V., Hullo M.-F., Lelong C., Schleich S., Sekowska A., Song B.H., Villani G., Kunst F., Danchin A., Glaser P.
    Microbiology 143:3313-3328(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  3. "Characterization of polyamine synthesis pathway in Bacillus subtilis 168."
    Sekowska A., Bertin P., Danchin A.
    Mol. Microbiol. 29:851-858(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION OF POLYAMINE PATHWAY.

Entry informationi

Entry nameiSPEB_BACSU
AccessioniPrimary (citable) accession number: P70999
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: February 1, 1997
Last modified: November 26, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3