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P70938 (TRPF_BACMQ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:BMQ_4320
OrganismBacillus megaterium (strain ATCC 12872 / QMB1551) [Complete proteome] [HAMAP]
Taxonomic identifier545693 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphoribosylanthranilate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154346

Sequences

Sequence LengthMass (Da)Tools
P70938 [UniParc].

Last modified August 10, 2010. Version 2.
Checksum: 3E4EF5CD8A1E869C

FASTA20823,399
        10         20         30         40         50         60 
MLIKYCGIRS KQDIALIEKS AATHIGFIFY PRSKRYVKPE RVNEFVTDEI KKQVSLVGVF 

        70         80         90        100        110        120 
VNTPVDQILE IASVTNLDVI QCHGQETAAD VRQLKQRGYE VWKALPHNKE TLQQMHVYEE 

       130        140        150        160        170        180 
ADGYVIDSKV KEQFGGTGVA FDWSFVPQYE SAAQRLGKKC FIAGGINACN IENLLPYQPG 

       190        200 
AIDISGGIET NGTKDYTKII EIERKIIL 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 12872 / QMB1551.
[2]Jablonski L.M., Vary P.S., Hudspeth D.S.
Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-113.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001983 Genomic DNA. Translation: ADE71330.1.
U67986 Genomic DNA. Translation: AAB07593.1.
RefSeqYP_003564764.1. NC_014019.1.

3D structure databases

ProteinModelPortalP70938.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE71330; ADE71330; BMQ_4320.
GeneID8988758.
KEGGbmq:BMQ_4320.
PATRIC35485408. VBIBacMeg35839_4364.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000161598.
KOK01817.
ProtClustDBCLSK2840596.

Enzyme and pathway databases

BioCycBMEG545693:GHSY-4320-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_BACMQ
AccessionPrimary (citable) accession number: P70938
Secondary accession number(s): D5DRF1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: August 10, 2010
Last modified: February 19, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways