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P70789 (KPYK1_AGRVI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate kinase

Short name=PK
EC=2.7.1.40
Gene names
Name:ttuE
Encoded onPlasmid pTrAB3
OrganismAgrobacterium vitis (Rhizobium vitis)
Taxonomic identifier373 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacterium

Protein attributes

Sequence length474 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor

Magnesium.

Potassium.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Subunit structure

Homotetramer By similarity.

Induction

By tartrate.

Sequence similarities

Belongs to the pyruvate kinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 474474Pyruvate kinase
PRO_0000112051

Sites

Metal binding391Potassium By similarity
Metal binding411Potassium By similarity
Metal binding711Potassium By similarity
Metal binding2221Magnesium By similarity
Metal binding2461Magnesium By similarity
Binding site371Substrate By similarity
Binding site2451Substrate; via amide nitrogen By similarity
Binding site2461Substrate; via amide nitrogen By similarity
Binding site2781Substrate By similarity
Site2201Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
P70789 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 4CCF84BCDB5AF546

FASTA47450,664
        10         20         30         40         50         60 
MFIRSNRRAK IVATVGPASS SPAILRSLFL AGVDTFRLNF SHGSRDDHAA AYRHIRALEK 

        70         80         90        100        110        120 
ELGTSIGILQ DLQGPKIRIG VLHEGRLQLT KDAEIRFVCG TEPGRGLMDI PLPHREIFAA 

       130        140        150        160        170        180 
VKPGDDLLID DGRVRVRALG VSDEFIDAKV IVAGPISNRK GVNLPGTVLD ISPLTPKDRK 

       190        200        210        220        230        240 
DLEFGLELGV DWIALSFVQT ARDMIEARSL VSDRAGLIAK IEKPSALDEI DDIVALSDAI 

       250        260        270        280        290        300 
MVARGDLGVE IPPEDVPGRQ KELIRACRIA AKPVIVATQM LDSMVTSPTP TRAEASDVAG 

       310        320        330        340        350        360 
AIYDGADAVM LSAESATGAF PVETVEIMSR IIEKTEKHKF YRPILEATEP QIAHTPPHAV 

       370        380        390        400        410        420 
ATAAADVALA LKAPVIVAFT VSGTTASRIS RARPPLPILA LTPSEQTARQ LGLMWGVVSL 

       430        440        450        460        470 
LSPTVDTYEQ SVDRATQAAV QTGLAEKSDQ IVVVTGFPFA TAGSTNNLRV TQAG 

« Hide

References

[1]"Characterization and distribution of tartrate utilization genes in the grapevine pathogen Agrobacterium vitis."
Salomone J.-Y., Crouzet P., de Ruffray P., Otten L.
Mol. Plant Microbe Interact. 9:401-408(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: AB3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U32375 Genomic DNA. Translation: AAB61625.1.

3D structure databases

ProteinModelPortalP70789.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Family and domain databases

Gene3D2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPYK1_AGRVI
AccessionPrimary (citable) accession number: P70789
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: June 11, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways