Reviewed, UniProtKB/Swiss-Prot P70744 (DEXT_ARTGO)

Names and origin

Protein names	Recommended name:     Dextranase     EC=3.2.1.11 Alternative name(s):     Alpha-1,6-glucan-6-glucanohydrolase     Endodextranase
Organism	Arthrobacter globiformis
Taxonomic identifier	1665 [NCBI]
Taxonomic lineage	Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	640 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->6)-alpha-D-glucosidic linkages in dextran.
Subcellular location	Secreted.
Sequence similarities	Belongs to the glycosyl hydrolase 49 family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dextranase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 32	32	Potential
	Chain	33 – 640	608	Dextranase		PRO_0000012210

Sequences

	Sequence		Length	Mass (Da)
	P70744-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 4AC7864A96A537D2	FASTA	640	71,143
	10 20 30 40 50 60 MPGTGLGRLA KHVTAAAAVF LISTGAVLPA QAETAPGSTP SAAPAASVEK HPITTANNGN 70 80 90 100 110 120 LHTWWHDNGV FSPAAPTQSD EVRRSSLYDV RVAQANQPQK AYDAFTYMSI PRSGKGKIGY 130 140 150 160 170 180 TEEDGAEFSS EAGLTMSWSS FEYAKDVWVE VSLRTGQTIS SADQVQIRPS SYNFEKQLVD 190 200 210 220 230 240 ADTVRIKVPY SDAGYRFSVE FEPQLYTAYN DMSGDSGKLT TEAEGNRPIH TEPRNSMMVF 250 260 270 280 290 300 AEPKLRGEQK ERLVPTQESG SIHYPEPGEV RNLNSVSAEI IYFRPGTYSM GSDYHAVLPA 310 320 330 340 350 360 NVKWVYLAPG AYVKGAFRFL HDTQSQYKVT GYGVLSGEQY VYEADTNNSY NHLSGASNCH 370 380 390 400 410 420 SSCVKMLQFA SADAEQKLDL QGVTVAEPPY HSFVVYGNEQ TFHMNVENYK QVGSWYWQTD 430 440 450 460 470 480 GIELYQGSTM KNTFFNANDD VLKMYHSDVS IDNTVVWKNE NGPVVQWGWT PRNIDNVNVT 490 500 510 520 530 540 NTTVIHNRMY WKDVKYNTCI FNSSSHWEDM GSTTKADPNT TVKNMRFENT TVEGMTNCAI 550 560 570 580 590 600 RVYALSDTEN IHIKNFNIGS WNGLDWTSQV SHLKRYTNSA GEKVTIGNEL PDGNGLAIEN 610 620 630 640 YSVGGQVIEK SGGNWSDYQL GRLGFDGENW DSWNAWKSAP

References

[1]	Oguma T., Kurokawa T., Tobe K., Kitao S., Kobayashi M. Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: T-3044.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D88361 Genomic DNA. Translation: BAA13596.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH49. Glycoside Hydrolase Family 49.
Enzyme and pathway databases
BRENDA	3.2.1.11. 1012.
Family and domain databases
InterPro	IPR005192. Glyco_hydro_49. IPR012334. Pectin_lyas_fold. IPR011050. Pectin_lyase_fold/virulence. [Graphical view]
Gene3D	G3DSA:2.160.20.10. Pectin_lyas_fold. 1 hit.
Pfam	PF03718. Glyco_hydro_49. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DEXT_ARTGO

Accession

Primary (citable) accession number: P70744

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	February 1, 1997
Last modified:	November 24, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)