ID   P70643_RAT              Unreviewed;       542 AA.
AC   P70643;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   08-NOV-2023, entry version 115.
DE   SubName: Full=Receptor type protein tyrosine phosphatase psi {ECO:0000313|EMBL:AAB42210.1};
DE   Flags: Fragment;
GN   Name=RPTPpsi {ECO:0000313|EMBL:AAB42210.1};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|EMBL:AAB42210.1};
RN   [1] {ECO:0000313|EMBL:AAB42210.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Sprague-Dawley {ECO:0000313|EMBL:AAB42210.1};
RX   PubMed=8989520;
RX   DOI=10.1002/(SICI)1097-0177(199701)208:1<48::AID-AJA5>3.0.CO;2-1;
RA   Sommer L., Rao M., Anderson D.J.;
RT   "RPTP delta and the novel protein tyrosine phosphatase RPTP psi are
RT   expressed in restricted regions of the developing central nervous system.";
RL   Dev. Dyn. 208:48-61(1997).
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DR   EMBL; U66566; AAB42210.1; -; mRNA.
DR   AlphaFoldDB; P70643; -.
DR   UCSC; RGD:620782; rat.
DR   PhylomeDB; P70643; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR   PANTHER; PTHR19134:SF207; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE U; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:AAB42210.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        144..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          317..542
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          463..534
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          227..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAB42210.1"
FT   NON_TER         542
FT                   /evidence="ECO:0000313|EMBL:AAB42210.1"
SQ   SEQUENCE   542 AA;  61232 MW;  90C7F8B3B733EC68 CRC64;
     GESENTITVL LRPAQGRGAP ISAYQVVVEE ERPRRLRREP GGQDCFSVPL TFETALARGL
     VHYFGAELAA SSLLEAMPFT VGDNQTYRGF WNPPLEPRKA YLIYFQAASH LEGETRLNCI
     RIARKAACKE SKRPLEVSQR SEEMGLILGI CAGGLVVLIL LLGAIIIIIR KGRDRYAYSY
     YPKPVNMAKA TVNYRQEKTH MMTAVDRSFT DQSTLQEDER LGLSFMDAPG YSPRGDQRSS
     GVTEASSLLG GSPRRPCGRK GSPYHTGQLH PAVRVADLLQ HINQMKTAEG YGFKQEYESF
     FEGWDATKKK DKLKSGRQEP VSAYDRHRVK LHPMLGDPDA DYISANYIDG YHRPNHFIAT
     QGPKPEMIYD FWRMVWQEQC VSVVMISKLV EVGRVKCSRY WPEHSDMYGD IKITLVKTET
     LAEYVVRTFA LERRGYSARH EVRQFHFTAW PEHGVPYHAT GLLAFIRRVK ASTPPDAGPV
     VIHCSAGTGR TGCYIVLDVM LDMAECEGVV DIYNCVKTLC SRRVNMIQTE EQYIFIHDAI
     LE
//