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Protein
Submitted name:

Receptor type protein tyrosine phosphatase psi

Gene

Ptpru

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: InterPro

GO - Biological processi

  1. neuron differentiation Source: RGD
  2. organ regeneration Source: RGD
  3. response to glucocorticoid Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation, ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor type protein tyrosine phosphatase psiImported
Gene namesi
Name:PtpruImported
Synonyms:RPTPpsiImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620782. Ptpru.

PTM / Processingi

Proteomic databases

PaxDbiP70643.

Expressioni

Gene expression databases

GenevestigatoriP70643.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030956.

Structurei

3D structure databases

ProteinModelPortaliP70643.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG5599.
HOGENOMiHOG000049029.
PhylomeDBiP70643.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P70643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GESENTITVL LRPAQGRGAP ISAYQVVVEE ERPRRLRREP GGQDCFSVPL
60 70 80 90 100
TFETALARGL VHYFGAELAA SSLLEAMPFT VGDNQTYRGF WNPPLEPRKA
110 120 130 140 150
YLIYFQAASH LEGETRLNCI RIARKAACKE SKRPLEVSQR SEEMGLILGI
160 170 180 190 200
CAGGLVVLIL LLGAIIIIIR KGRDRYAYSY YPKPVNMAKA TVNYRQEKTH
210 220 230 240 250
MMTAVDRSFT DQSTLQEDER LGLSFMDAPG YSPRGDQRSS GVTEASSLLG
260 270 280 290 300
GSPRRPCGRK GSPYHTGQLH PAVRVADLLQ HINQMKTAEG YGFKQEYESF
310 320 330 340 350
FEGWDATKKK DKLKSGRQEP VSAYDRHRVK LHPMLGDPDA DYISANYIDG
360 370 380 390 400
YHRPNHFIAT QGPKPEMIYD FWRMVWQEQC VSVVMISKLV EVGRVKCSRY
410 420 430 440 450
WPEHSDMYGD IKITLVKTET LAEYVVRTFA LERRGYSARH EVRQFHFTAW
460 470 480 490 500
PEHGVPYHAT GLLAFIRRVK ASTPPDAGPV VIHCSAGTGR TGCYIVLDVM
510 520 530 540
LDMAECEGVV DIYNCVKTLC SRRVNMIQTE EQYIFIHDAI LE
Length:542
Mass (Da):61,232
Last modified:January 31, 1997 - v1
Checksum:i90C7F8B3B733EC68
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei542 – 5421Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66566 mRNA. Translation: AAB42210.1.
UniGeneiRn.35625.

Genome annotation databases

UCSCiRGD:620782. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66566 mRNA. Translation: AAB42210.1.
UniGeneiRn.35625.

3D structure databases

ProteinModelPortaliP70643.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030956.

Proteomic databases

PaxDbiP70643.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:620782. rat.

Organism-specific databases

RGDi620782. Ptpru.

Phylogenomic databases

eggNOGiCOG5599.
HOGENOMiHOG000049029.
PhylomeDBiP70643.

Gene expression databases

GenevestigatoriP70643.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "RPTP delta and the novel protein tyrosine phosphatase RPTP psi are expressed in restricted regions of the developing central nervous system."
    Sommer L., Rao M., Anderson D.J.
    Dev. Dyn. 208:48-61(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiP70643_RAT
AccessioniPrimary (citable) accession number: P70643
Entry historyi
Integrated into UniProtKB/TrEMBL: January 31, 1997
Last sequence update: January 31, 1997
Last modified: October 28, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.