P70643 (P70643_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Receptor type protein tyrosine phosphatase psi EMBL AAB42210.1

Gene names

Name:	Ptpru RGD 620782
Synonyms:	RPTPpsi EMBL AAB42210.1

Organism

Rattus norvegicus (Rat) EMBL AAB42210.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	542 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. SAAS SAAS016130
Sequence similarities	Contains 1 tyrosine-protein phosphatase domain. SAAS SAAS000387

Ontologies

Keywords
Molecular function	Hydrolase Protein phosphatase SAAS SAAS016130 Receptor EMBL AAB42210.1
Gene Ontology (GO)
Biological_process	neuron differentiation Non-traceable author statement Ref.1. Source: RGD organ regeneration Inferred from expression pattern PubMed 7591957. Source: RGD peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC response to glucocorticoid stimulus Inferred from expression pattern PubMed 17457373. Source: RGD
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAB42210.1
	Non-terminal residue	542	1	EMBL AAB42210.1

Sequences

	Sequence		Length	Mass (Da)
	P70643 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 90C7F8B3B733EC68	FASTA	542	61,232
	10 20 30 40 50 60 GESENTITVL LRPAQGRGAP ISAYQVVVEE ERPRRLRREP GGQDCFSVPL TFETALARGL 70 80 90 100 110 120 VHYFGAELAA SSLLEAMPFT VGDNQTYRGF WNPPLEPRKA YLIYFQAASH LEGETRLNCI 130 140 150 160 170 180 RIARKAACKE SKRPLEVSQR SEEMGLILGI CAGGLVVLIL LLGAIIIIIR KGRDRYAYSY 190 200 210 220 230 240 YPKPVNMAKA TVNYRQEKTH MMTAVDRSFT DQSTLQEDER LGLSFMDAPG YSPRGDQRSS 250 260 270 280 290 300 GVTEASSLLG GSPRRPCGRK GSPYHTGQLH PAVRVADLLQ HINQMKTAEG YGFKQEYESF 310 320 330 340 350 360 FEGWDATKKK DKLKSGRQEP VSAYDRHRVK LHPMLGDPDA DYISANYIDG YHRPNHFIAT 370 380 390 400 410 420 QGPKPEMIYD FWRMVWQEQC VSVVMISKLV EVGRVKCSRY WPEHSDMYGD IKITLVKTET 430 440 450 460 470 480 LAEYVVRTFA LERRGYSARH EVRQFHFTAW PEHGVPYHAT GLLAFIRRVK ASTPPDAGPV 490 500 510 520 530 540 VIHCSAGTGR TGCYIVLDVM LDMAECEGVV DIYNCVKTLC SRRVNMIQTE EQYIFIHDAI LE

References

[1]	"RPTP delta and the novel protein tyrosine phosphatase RPTP psi are expressed in restricted regions of the developing central nervous system." Sommer L., Rao M., Anderson D.J. Dev. Dyn. 208:48-61(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Sprague-Dawley EMBL AAB42210.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U66566 mRNA. Translation: AAB42210.1.
IPI	IPI00190595.
UniGene	Rn.35625.
3D structure databases
HSSP	HSSP built from PDB template 1RPM based on UniProtKB P28827.
ProteinModelPortal	P70643.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000030956.
Proteomic databases
PaxDb	P70643.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	RGD:620782. rat.
Organism-specific databases
RGD	620782. Ptpru.
Phylogenomic databases
eggNOG	COG5599.
HOGENOM	HOG000049029.
InParanoid	P70643.
OrthoDB	EOG4868BM.
Gene expression databases
Genevestigator	P70643.
Family and domain databases
InterPro	IPR000387. Tyr/Dual-sp_Pase. IPR016130. Tyr_Pase_AS. IPR000242. Tyr_Pase_rcpt/non-rcpt. [Graphical view]
Pfam	PF00102. Y_phosphatase. 1 hit. [Graphical view]
PRINTS	PR00700. PRTYPHPHTASE.
SMART	SM00194. PTPc. 1 hit. [Graphical view]
PROSITE	PS00383. TYR_PHOSPHATASE_1. 1 hit. PS50056. TYR_PHOSPHATASE_2. 1 hit. PS50055. TYR_PHOSPHATASE_PTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P70643_RAT

Accession

Primary (citable) accession number: P70643

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 1997
Last sequence update:	February 1, 1997
Last modified:	April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)