P70616 (P70616_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lost on transformation EMBL AAB67042.1

Submitted name:
Protein Plagl1 Ensembl ENSRNOP00000030918

Gene names

Name:	Plagl1 RGD 3014 Ensembl ENSRNOP00000030918
Synonyms:	Lot1 EMBL AAB67042.1

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell differentiation Inferred from Biological aspect of Ancestor. Source: RefGenome induction of apoptosis Inferred from Biological aspect of Ancestor. Source: RefGenome positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara
Cellular_component	nucleus Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	DNA binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding RNA polymerase II transcription factor activity Inferred from Biological aspect of Ancestor. Source: RefGenome zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	P70616 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 8501071AADFB3F4B	FASTA	583	65,960
	10 20 30 40 50 60 MAPFRCQKCG KSFLTLEKFT IHNYSHTRER PFKCSKTECG KAFVSKYKLM RHMATHSPQK 70 80 90 100 110 120 THQCTHCEKT FNRKDHLKNH LQTHDPNKMI YACEDCGKKY HTMLGYKRHM ALHSASSGDL 130 140 150 160 170 180 TCGVCTLELG STEVLLDHLK SHAEEKAHHA PREKKHQCDH CERCFYTRKD VRRHLVVHTG 190 200 210 220 230 240 CKDFLCQFCA QRFGRKDHLT RHTKKTHSQE LMQESLQAGE YQGGYQPIAP PFQIKADPMP 250 260 270 280 290 300 PFQLEMPPES GLDGGLPPEI HGLVLASPEE VPQPMLSMPP MQPMPEQPFT LHPGVVPSSP 310 320 330 340 350 360 PPIILQEHKY SPVPTSFAPF VSMPMKADLK GFCNMGLFEE FPLQECQSPV KFSQCFEMAK 370 380 390 400 410 420 EGFGKVTLPK ELLVDAVNIA IPGSLEISSL LGFWQLPPPP PQNGFMNGTI PVGAGEPLPH 430 440 450 460 470 480 RITCLAQQQP PPLLPPPPPL PLPEPLPQPQ LPPQFQLQLQ PQPQMQPQMQ LQPLQLQLPQ 490 500 510 520 530 540 LLPQLQPEPE PEPEPEEEEE EEEEIEEEEE IEEEEEAEPE AEEEEEAEDE EEAEEEEEEP 550 560 570 580 QPEEAQIAMS AVNMGQPPLP PTPHVFTAGT NTAILPHFHH AFR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells." Abdollahi A., Godwin A.K., Miller P.D., Getts L.A., Schultz D.C., Taguchi T., Testa J.R., Hamilton T.C. Cancer Res. 57:2029-2034(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Ovary EMBL AAB67042.1.
[2]	"Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors." Abdollahi A., Roberts D., Godwin A.K., Schultz D.C., Sonoda G., Testa J.R., Hamilton T.C. Oncogene 14:1973-1979(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Ovary EMBL AAB67042.1.
[3]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000030918.
[4]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000030918.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06000387 Genomic DNA. No translation available. AABR06000388 Genomic DNA. No translation available. U72620 mRNA. Translation: AAB67042.1.
IPI	IPI00190528.
RefSeq	NP_036892.1. NM_012760.3.
UniGene	Rn.6977.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000030918.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000030329; ENSRNOP00000030918; ENSRNOG00000025587.
GeneID	25157.
KEGG	rno:25157.
UCSC	RGD:3014. rat.
Organism-specific databases
CTD	5325.
RGD	3014. Plagl1.
Phylogenomic databases
eggNOG	COG5048.
GeneTree	ENSGT00390000013640.
HOGENOM	HOG000294191.
HOVERGEN	HBG053608.
InParanoid	P70616.
OMA	MLPMQPM.
OrthoDB	EOG48WC1V.
Gene expression databases
Genevestigator	P70616.
Family and domain databases
Gene3D	3.30.160.60. 5 hits.
InterPro	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
SMART	SM00355. ZnF_C2H2. 7 hits. [Graphical view]
PROSITE	PS00028. ZINC_FINGER_C2H2_1. 7 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	605619.

Entry information

Entry name

P70616_RAT

Accession

Primary (citable) accession number: P70616

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)