Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

KRAB-zinc finger protein KZF-2

Gene

Zfp455

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
KRAB-zinc finger protein KZF-2Imported
Gene namesi
Name:Zfp455Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi628788. Zfp455.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiP70591.

Expressioni

Gene expression databases

GenevisibleiP70591. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049638.

Structurei

3D structure databases

ProteinModelPortaliP70591.
SMRiP70591. Positions 106-160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 7672KRABInterPro annotationAdd
BLAST
Domaini109 – 13628C2H2-typeInterPro annotationAdd
BLAST
Domaini137 – 16428C2H2-typeInterPro annotationAdd
BLAST
Domaini165 – 19228C2H2-typeInterPro annotationAdd
BLAST
Domaini193 – 22028C2H2-typeInterPro annotationAdd
BLAST
Domaini247 – 27428C2H2-typeInterPro annotationAdd
BLAST
Domaini275 – 30228C2H2-typeInterPro annotationAdd
BLAST
Domaini303 – 33028C2H2-typeInterPro annotationAdd
BLAST
Domaini331 – 35828C2H2-typeInterPro annotationAdd
BLAST
Domaini359 – 38628C2H2-typeInterPro annotationAdd
BLAST
Domaini387 – 41428C2H2-typeInterPro annotationAdd
BLAST
Domaini415 – 44228C2H2-typeInterPro annotationAdd
BLAST
Domaini443 – 47028C2H2-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains KRAB domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
KOiK09228.
PhylomeDBiP70591.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 12 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 12 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P70591-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEMLSFWDV AIDFSPEEWE CLEPVQWNLY RDVMLENYSN FVFLGLTFSK
60 70 80 90 100
PFLVTFLEQG QGPWDMQRQA AAAVHPGIAL NDPNCYSKTT NCKSLLIKRR
110 120 130 140 150
KLHIGEKPYK CEECGKALGS LKTLSIHQRL HTGDKPYKCK ECHKAFSTRS
160 170 180 190 200
ALFIHMKNHT DEKTHKCEEC GRLFYYPSML KQHQRIHSRV KPYKCQECGK
210 220 230 240 250
AFTDPSFLKK HQKIHFRKHT YQFKECVKRF SPPIHLQEQI HTGQKPFKCG
260 270 280 290 300
ECFKAFHNHL ALRKHQTVHF GEKPYKCEEC GRCYSTSFYL RRHQTIHSKY
310 320 330 340 350
KSYKCEHCGR CYSSTSCLKR HQTIHSEDNP YKCEECGKYF SSSTCLRTHQ
360 370 380 390 400
TVHSVDNSYK CDECGRYYSS SLSLTRHQII HSEDNPYKCE ECGKRFSCSA
410 420 430 440 450
SLQEHQTIHT GEKPYECENC HKAFRHHSSL RKHKTVHTGE KPYKCEKCGR
460 470 480
CFSRHSCLRI HQAIHSDGKI PSVWNVVNLC
Length:480
Mass (Da):56,354
Last modified:February 1, 1997 - v1
Checksum:i4E4929507BF5012D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67083 mRNA. Translation: AAC61662.1.
RefSeqiNP_775436.2. NM_173314.2.
UniGeneiRn.10664.

Genome annotation databases

GeneIDi286979.
KEGGirno:286979.
UCSCiRGD:628788. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67083 mRNA. Translation: AAC61662.1.
RefSeqiNP_775436.2. NM_173314.2.
UniGeneiRn.10664.

3D structure databases

ProteinModelPortaliP70591.
SMRiP70591. Positions 106-160.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049638.

Proteomic databases

PaxDbiP70591.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi286979.
KEGGirno:286979.
UCSCiRGD:628788. rat.

Organism-specific databases

CTDi218311.
RGDi628788. Zfp455.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
KOiK09228.
PhylomeDBiP70591.

Miscellaneous databases

NextBioi625221.

Gene expression databases

GenevisibleiP70591. RN.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 12 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 12 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Kzf1 - a novel KRAB zinc finger protein encoding gene expressed during rat spermatogenesis."
    Bellefroid E.J., Sahin M., Poncelet D.A., Riviere M., Bourguignon C., Martial J.A., Morris P.L., Pieler T., Szpirer C., Ward D.C.
    Biochim. Biophys. Acta 1398:321-329(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP70591_RAT
AccessioniPrimary (citable) accession number: P70591
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.