##gff-version 3
P70380	UniProtKB	Propeptide	1	35	.	.	.	ID=PRO_0000015345;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7477296;Dbxref=PMID:7477296	
P70380	UniProtKB	Chain	36	192	.	.	.	ID=PRO_0000015346;Note=Interleukin-18	
P70380	UniProtKB	Site	35	36	.	.	.	Note=Cleavage%3B by CASP1;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q14116	
P70380	UniProtKB	Site	69	70	.	.	.	Note=Cleavage%3B by CASP3;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q14116	
P70380	UniProtKB	Mutagenesis	28	31	.	.	.	Note=Humanized protein that is efficiently cleaved by Casp4/Casp11%3B when associated with 36-Y--E-41. ENGD->DDEN;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:37993712;Dbxref=PMID:37993712	
P70380	UniProtKB	Mutagenesis	36	41	.	.	.	Note=Humanized protein that is efficiently cleaved by Casp4/Casp11%3B when associated with 28-D--N-41. NFGRLH->YFGRLE;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:37993712;Dbxref=PMID:37993712	
P70380	UniProtKB	Sequence conflict	183	185	.	.	.	Note=MFT->IS;Ontology_term=ECO:0000305;evidence=ECO:0000305