ID   P70260_MOUSE            Unreviewed;       119 AA.
AC   P70260;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 142.
DE   SubName: Full=Oct11 POU-box protein (119 AA) {ECO:0000313|EMBL:CAA36219.1};
DE   Flags: Fragment;
GN   Name=Pou2f3 {ECO:0000313|MGI:MGI:102565};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:CAA36219.1};
RN   [1] {ECO:0000313|EMBL:CAA36219.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=t6/tw1 {ECO:0000313|EMBL:CAA36219.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:CAA36219.1};
RX   PubMed=1970171; DOI=10.1093/nar/18.6.1634;
RA   Goldsborough A., Ashworth A., Willison K.R.;
RT   "Cloning and sequencing of POU-boxes expressed in mouse testis.";
RL   Nucleic Acids Res. 18:1634-1634(1990).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR   EMBL; X51960; CAA36219.1; -; mRNA.
DR   PIR; JC2002; JC2002.
DR   AlphaFoldDB; P70260; -.
DR   PeptideAtlas; P70260; -.
DR   AGR; MGI:102565; -.
DR   MGI; MGI:102565; Pou2f3.
DR   ChiTaRS; Pou2f3; mouse.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR013847; POU.
DR   InterPro; IPR000327; POU_dom.
DR   PANTHER; PTHR11636; POU DOMAIN; 1.
DR   PANTHER; PTHR11636:SF81; POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF00157; Pou; 1.
DR   PRINTS; PR00028; POUDOMAIN.
DR   SMART; SM00352; POU; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS00465; POU_2; 1.
DR   PROSITE; PS51179; POU_3; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..51
FT                   /note="POU-specific"
FT                   /evidence="ECO:0000259|PROSITE:PS51179"
FT   DOMAIN          73..119
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   REGION          49..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAA36219.1"
FT   NON_TER         119
FT                   /evidence="ECO:0000313|EMBL:CAA36219.1"
SQ   SEQUENCE   119 AA;  13424 MW;  49B70EEB65CE5EDB CRC64;
     FTQGDVGLAM GKLYGNDFSQ TTISRFEALN LSFKNMCKLK PLLEKWLNDA ESSPSDPSAS
     TPSSYPTLSE VFGRKRKKRT SIETNIRLTL EKRFQDNPKP SSEEISMIAE QLSMEKEVV
//