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P70260

- P70260_MOUSE

UniProt

P70260 - P70260_MOUSE

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Protein
Submitted name:

Oct11 POU-box protein (119 AA)

Gene
Pou2f3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. protein dimerization activity Source: MGI
  3. sequence-specific DNA binding Source: MGI
  4. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. epidermis development Source: MGI
  2. keratinocyte differentiation Source: MGI
  3. negative regulation by host of viral transcription Source: Ensembl
  4. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  5. wound healing Source: MGI
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Oct11 POU-box protein (119 AA)Imported
Gene namesi
Name:Pou2f3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102565. Pou2f3.

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nucleus Source: UniProtKB-SubCell
  3. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotationsImported

Expressioni

Gene expression databases

ArrayExpressiP70260.
BgeeiP70260.
GenevestigatoriP70260.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034513.

Structurei

3D structure databases

ProteinModelPortaliP70260.

Family & Domainsi

Sequence similaritiesi

Contains POU-specific domain.SAAS annotations
Contains homeobox DNA-binding domain.SAAS annotations

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotations

Phylogenomic databases

HOVERGENiHBG053120.
InParanoidiP70260.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P70260-1 [UniParc]FASTAAdd to Basket

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FTQGDVGLAM GKLYGNDFSQ TTISRFEALN LSFKNMCKLK PLLEKWLNDA    50
ESSPSDPSAS TPSSYPTLSE VFGRKRKKRT SIETNIRLTL EKRFQDNPKP 100
SSEEISMIAE QLSMEKEVV 119
Length:119
Mass (Da):13,424
Last modified:February 1, 1997 - v1
Checksum:i49B70EEB65CE5EDB
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei119 – 1191Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X51960 mRNA. Translation: CAA36219.1.
PIRiJC2002.
UniGeneiMm.436650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X51960 mRNA. Translation: CAA36219.1 .
PIRi JC2002.
UniGenei Mm.436650.

3D structure databases

ProteinModelPortali P70260.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000034513.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:102565. Pou2f3.

Phylogenomic databases

HOVERGENi HBG053120.
InParanoidi P70260.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi P70260.
Bgeei P70260.
Genevestigatori P70260.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProi IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view ]
PRINTSi PR00028. POUDOMAIN.
SMARTi SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEi PS50071. HOMEOBOX_2. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and sequencing of POU-boxes expressed in mouse testis."
    Goldsborough A., Ashworth A., Willison K.R.
    Nucleic Acids Res. 18:1634-1634(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: t6/tw1Imported.
    Tissue: TestesImported.

Entry informationi

Entry nameiP70260_MOUSE
AccessioniPrimary (citable) accession number: P70260
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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