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P70260

- P70260_MOUSE

UniProt

P70260 - P70260_MOUSE

Protein
Submitted name:

Oct11 POU-box protein (119 AA)

Gene

Pou2f3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. protein dimerization activity Source: MGI
    3. sequence-specific DNA binding Source: MGI
    4. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. epidermis development Source: MGI
    2. keratinocyte differentiation Source: MGI
    3. negative regulation by host of viral transcription Source: Ensembl
    4. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    5. wound healing Source: MGI

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Oct11 POU-box protein (119 AA)Imported
    Gene namesi
    Name:Pou2f3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:102565. Pou2f3.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. nucleus Source: UniProtKB-SubCell
    3. transcription factor complex Source: MGI

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotationImported

    Expressioni

    Gene expression databases

    ArrayExpressiP70260.
    BgeeiP70260.
    GenevestigatoriP70260.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000034513.

    Structurei

    3D structure databases

    ProteinModelPortaliP70260.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains POU-specific domain.SAAS annotation
    Contains homeobox DNA-binding domain.SAAS annotation

    Keywords - Domaini

    HomeoboxUniRule annotationSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG053120.
    InParanoidiP70260.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProiIPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view]
    PRINTSiPR00028. POUDOMAIN.
    SMARTiSM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEiPS50071. HOMEOBOX_2. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P70260-1 [UniParc]FASTAAdd to Basket

    « Hide

    FTQGDVGLAM GKLYGNDFSQ TTISRFEALN LSFKNMCKLK PLLEKWLNDA    50
    ESSPSDPSAS TPSSYPTLSE VFGRKRKKRT SIETNIRLTL EKRFQDNPKP 100
    SSEEISMIAE QLSMEKEVV 119
    Length:119
    Mass (Da):13,424
    Last modified:February 1, 1997 - v1
    Checksum:i49B70EEB65CE5EDB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei119 – 1191Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X51960 mRNA. Translation: CAA36219.1.
    PIRiJC2002.
    UniGeneiMm.436650.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X51960 mRNA. Translation: CAA36219.1 .
    PIRi JC2002.
    UniGenei Mm.436650.

    3D structure databases

    ProteinModelPortali P70260.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000034513.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:102565. Pou2f3.

    Phylogenomic databases

    HOVERGENi HBG053120.
    InParanoidi P70260.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P70260.
    Bgeei P70260.
    Genevestigatori P70260.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProi IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view ]
    PRINTSi PR00028. POUDOMAIN.
    SMARTi SM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEi PS50071. HOMEOBOX_2. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing of POU-boxes expressed in mouse testis."
      Goldsborough A., Ashworth A., Willison K.R.
      Nucleic Acids Res. 18:1634-1634(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: t6/tw1Imported.
      Tissue: TestesImported.

    Entry informationi

    Entry nameiP70260_MOUSE
    AccessioniPrimary (citable) accession number: P70260
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)