##gff-version 3
P70174	UniProtKB	Chain	1	488	.	.	.	ID=PRO_0000069677;Note=Histamine H1 receptor	
P70174	UniProtKB	Topological domain	1	29	.	.	.	Note=Extracellular;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	30	52	.	.	.	Note=Helical%3B Name%3D1;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	53	62	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	63	83	.	.	.	Note=Helical%3B Name%3D2;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	84	101	.	.	.	Note=Extracellular;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	102	123	.	.	.	Note=Helical%3B Name%3D3;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	124	143	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	144	164	.	.	.	Note=Helical%3B Name%3D4;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	165	189	.	.	.	Note=Extracellular;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	190	210	.	.	.	Note=Helical%3B Name%3D5;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	211	417	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	418	439	.	.	.	Note=Helical%3B Name%3D6;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	440	451	.	.	.	Note=Extracellular;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Transmembrane	452	471	.	.	.	Note=Helical%3B Name%3D7;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Topological domain	472	488	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Region	107	112	.	.	.	Note=Important for agonist binding;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Region	245	337	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P70174	UniProtKB	Region	425	429	.	.	.	Note=Important for agonist binding;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P70174	UniProtKB	Compositional bias	245	260	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P70174	UniProtKB	Compositional bias	269	293	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P70174	UniProtKB	Compositional bias	321	337	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P70174	UniProtKB	Modified residue	140	140	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P35367	
P70174	UniProtKB	Modified residue	142	142	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P35367	
P70174	UniProtKB	Modified residue	230	230	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P35367	
P70174	UniProtKB	Modified residue	344	344	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P70174	UniProtKB	Modified residue	347	347	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P70174	UniProtKB	Modified residue	381	381	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P70174	UniProtKB	Modified residue	383	383	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P70174	UniProtKB	Modified residue	397	397	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P35367	
P70174	UniProtKB	Modified residue	399	399	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P35367	
P70174	UniProtKB	Glycosylation	5	5	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P70174	UniProtKB	Glycosylation	18	18	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P70174	UniProtKB	Disulfide bond	100	180	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00521	
P70174	UniProtKB	Disulfide bond	442	445	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00521	
P70174	UniProtKB	Natural variant	263	263	.	.	.	Note=In strain: C3H/HeJ and CBA/J. P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12142541;Dbxref=PMID:12142541	
P70174	UniProtKB	Natural variant	312	312	.	.	.	Note=In strain: C3H/HeJ and CBA/J. V->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12142541;Dbxref=PMID:12142541	
P70174	UniProtKB	Natural variant	330	330	.	.	.	Note=In strain: C3H/HeJ and CBA/J. P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12142541;Dbxref=PMID:12142541	
P70174	UniProtKB	Sequence conflict	2	2	.	.	.	Note=S->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	47	47	.	.	.	Note=L->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	79	79	.	.	.	Note=V->I;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	215	216	.	.	.	Note=KA->NG;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	224	224	.	.	.	Note=R->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	242	242	.	.	.	Note=E->D;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	244	244	.	.	.	Note=A->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	261	261	.	.	.	Note=K->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	278	278	.	.	.	Note=E->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P70174	UniProtKB	Sequence conflict	379	379	.	.	.	Note=S->R;Ontology_term=ECO:0000305;evidence=ECO:0000305