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Protein

Nucleoside diphosphate kinase

Gene

nme2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside diphosphate kinaseUniRule annotation (EC:2.7.4.6UniRule annotation)
Gene namesi
Name:nme2Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-923251. nme2.

Structurei

3D structure databases

SMRiP70071. Positions 3-153.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NDK family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG000423.

Family and domain databases

HAMAPiMF_00451. NDP_kinase. 1 hit.
InterProiIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
PfamiPF00334. NDK. 1 hit.
[Graphical view]
PRINTSiPR01243. NUCDPKINASE.
SMARTiSM00562. NDK. 1 hit.
[Graphical view]
PROSITEiPS00469. NDP_KINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P70071-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAANKERTFI AIKPDGVQRG LIGDIIKRFE QKGFRLVAMK FQQASQDLLR
60 70 80 90 100
QHYIDLKDRP FYPGLVEYMS SGPVLAMVWE GLNVVKTGRV MLGETNPADS
110 120 130 140 150
KPGTIRGDFC IQVGRNIIHG SDSVESANKE IALWFKDEEL VENKSCAYEW

VYEN
Length:154
Mass (Da):17,471
Last modified:February 1, 1997 - v1
Checksum:iDDE3A076190F65F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97899 mRNA. Translation: CAA66473.1.
X97901 mRNA. Translation: CAA66475.1.
RefSeqiNP_001081044.1. NM_001087575.1.
UniGeneiXl.2830.

Genome annotation databases

GeneIDi394350.
KEGGixla:394350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97899 mRNA. Translation: CAA66473.1.
X97901 mRNA. Translation: CAA66475.1.
RefSeqiNP_001081044.1. NM_001087575.1.
UniGeneiXl.2830.

3D structure databases

SMRiP70071. Positions 3-153.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi394350.
KEGGixla:394350.

Organism-specific databases

CTDi394350.
XenbaseiXB-GENE-923251. nme2.

Phylogenomic databases

HOVERGENiHBG000423.

Family and domain databases

HAMAPiMF_00451. NDP_kinase. 1 hit.
InterProiIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
PfamiPF00334. NDK. 1 hit.
[Graphical view]
PRINTSiPR01243. NUCDPKINASE.
SMARTiSM00562. NDK. 1 hit.
[Graphical view]
PROSITEiPS00469. NDP_KINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP70071_XENLA
AccessioniPrimary (citable) accession number: P70071
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.