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Protein
Submitted name:

Androgen receptor alpha isoform

Gene

ar

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi426 – 501Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Androgen receptor alpha isoformImported
Gene namesi
Name:arImported
Synonyms:Xl alpha ARImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-479433. ar.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliP70048.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini426 – 501Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG007583.
KOiK08557.

Family and domain databases

InterProiView protein in InterPro
IPR001103. Andrgn_rcpt.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
PfamiView protein in Pfam
PF02166. Androgen_recep. 2 hits.
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P70048-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVHIGLGGV YKQPPGKMIR GAFENLFLSV REALQGERRA LEGSQAPAGW
60 70 80 90 100
SEAPGTHRWS EASPQDGTPL NPWVTHPPAP WREAQAEAAP QNPAGRTEGA
110 120 130 140 150
QFPALGDCPT ELKEILGEQS GRILESEETP AEKEGFSGPP EGISDSAKEL
160 170 180 190 200
CKAVSVSLGL SMEALEHLSA GAGEAQQRGD CMYAHPPDTH KCQVAEEDKS
210 220 230 240 250
DTRDGPFRRS SQSNFATGKS PEDGGGGGGG SSSAGGSEEK EQPCTDLALP
260 270 280 290 300
EPAGGYRHRA MELTPSLTLY KPTAFMEESP GYPSRDFYSF QMALAPHGRI
310 320 330 340 350
KVENPMEYGG GAWGAAGRYS ELSGFAHCGA TAGWHTLFEE GQSSGSFAEA
360 370 380 390 400
GPYSYPRSHG PAGADGEFPS DAWYPAPTMI GRVPYSGPMK TEMAPWMEGY
410 420 430 440 450
PGAFGEMRLE GGRDHLLPID YYFPPQKTCL ICGDEASGCH YGALTCGSCK
460 470 480 490 500
VFFKRAAEGK QKYLCASRND CTIDKFRRKN CPSCRLRKCY EAGMTLGARK
510 520 530 540 550
LKKLGNLKAQ EELDGSSVQG EGSKELSPGM GIPQLEGYSC QPIFLNVLEA
560 570 580 590 600
IEPVVVCAGH DNNQPDSFAL LLSSLNELGE RQLVHVVKWA KALPGFRNLH
610 620 630 640 650
VSDQMTVIQY SWMGLMIFAM GWRSFKNVNS RMLYFAPDLV FNEYRMHKSR
660 670 680 690 700
MYSQCVRLRH LSQEFGWLQI TPEEFLCMKA LLLFSIIPVE GLKDQKCFDE
710 720 730 740 750
LRMNYIKELD RVISCKRNNP ASSSRRFFQL TKLLDSVQPI ARELHQFTFD
760 770 780 790
LFVKAQMVSV DYPEMMSEII SVQVPKILSG RVKPLYFHIS
Length:790
Mass (Da):86,974
Last modified:January 1, 1999 - v2
Checksum:i9E7FC136CCCC3906
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67129 mRNA. Translation: AAC97386.1.
RefSeqiNP_001084353.1. NM_001090884.1.
UniGeneiXl.426.

Genome annotation databases

GeneIDi399456.
KEGGixla:399456.

Similar proteinsi

Entry informationi

Entry nameiP70048_XENLA
AccessioniPrimary (citable) accession number: P70048
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: January 1, 1999
Last modified: September 27, 2017
This is version 115 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)