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Protein
Submitted name:

Androgen receptor alpha isoform

Gene

ar

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Androgen receptor alpha isoformImported
Gene namesi
Name:arImported
Synonyms:Xl alpha ARImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-479433. ar.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliP70048.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini426 – 501Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains 1 Nuclear receptor DNA-binding domain.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG007583.
KOiK08557.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR001103. Andrgn_rcpt.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF02166. Androgen_recep. 2 hits.
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P70048-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVHIGLGGV YKQPPGKMIR GAFENLFLSV REALQGERRA LEGSQAPAGW
60 70 80 90 100
SEAPGTHRWS EASPQDGTPL NPWVTHPPAP WREAQAEAAP QNPAGRTEGA
110 120 130 140 150
QFPALGDCPT ELKEILGEQS GRILESEETP AEKEGFSGPP EGISDSAKEL
160 170 180 190 200
CKAVSVSLGL SMEALEHLSA GAGEAQQRGD CMYAHPPDTH KCQVAEEDKS
210 220 230 240 250
DTRDGPFRRS SQSNFATGKS PEDGGGGGGG SSSAGGSEEK EQPCTDLALP
260 270 280 290 300
EPAGGYRHRA MELTPSLTLY KPTAFMEESP GYPSRDFYSF QMALAPHGRI
310 320 330 340 350
KVENPMEYGG GAWGAAGRYS ELSGFAHCGA TAGWHTLFEE GQSSGSFAEA
360 370 380 390 400
GPYSYPRSHG PAGADGEFPS DAWYPAPTMI GRVPYSGPMK TEMAPWMEGY
410 420 430 440 450
PGAFGEMRLE GGRDHLLPID YYFPPQKTCL ICGDEASGCH YGALTCGSCK
460 470 480 490 500
VFFKRAAEGK QKYLCASRND CTIDKFRRKN CPSCRLRKCY EAGMTLGARK
510 520 530 540 550
LKKLGNLKAQ EELDGSSVQG EGSKELSPGM GIPQLEGYSC QPIFLNVLEA
560 570 580 590 600
IEPVVVCAGH DNNQPDSFAL LLSSLNELGE RQLVHVVKWA KALPGFRNLH
610 620 630 640 650
VSDQMTVIQY SWMGLMIFAM GWRSFKNVNS RMLYFAPDLV FNEYRMHKSR
660 670 680 690 700
MYSQCVRLRH LSQEFGWLQI TPEEFLCMKA LLLFSIIPVE GLKDQKCFDE
710 720 730 740 750
LRMNYIKELD RVISCKRNNP ASSSRRFFQL TKLLDSVQPI ARELHQFTFD
760 770 780 790
LFVKAQMVSV DYPEMMSEII SVQVPKILSG RVKPLYFHIS
Length:790
Mass (Da):86,974
Last modified:January 1, 1999 - v2
Checksum:i9E7FC136CCCC3906
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67129 mRNA. Translation: AAC97386.1.
RefSeqiNP_001084353.1. NM_001090884.1.
UniGeneiXl.426.

Genome annotation databases

GeneIDi399456.
KEGGixla:399456.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67129 mRNA. Translation: AAC97386.1.
RefSeqiNP_001084353.1. NM_001090884.1.
UniGeneiXl.426.

3D structure databases

ProteinModelPortaliP70048.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399456.
KEGGixla:399456.

Organism-specific databases

CTDi367.
XenbaseiXB-GENE-479433. ar.

Phylogenomic databases

HOVERGENiHBG007583.
KOiK08557.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR001103. Andrgn_rcpt.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF02166. Androgen_recep. 2 hits.
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP70048_XENLA
AccessioniPrimary (citable) accession number: P70048
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: January 1, 1999
Last modified: November 30, 2016
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.