P70012 (P70012_XENLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nuclear/mitotic apparatus protein EMBL CAA68905.1

Gene names

Name:	numa1 Xenbase XB-FEAT-6259083 Xenbase XB-GENE-6252170 Xenbase XB-FEAT-6252170
Synonyms:	NuMA EMBL CAA68905.1

Organism

Xenopus laevis (African clawed frog) EMBL CAA68905.1

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	2253 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Sequences

	Sequence		Length	Mass (Da)
	P70012 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 158AEF149543E5B5	FASTA	2,253	256,797
	10 20 30 40 50 60 MTSHSGKMEA LLCWVNSLKV DEPIERFSQL QDLSILLKVV GVLSGNSEET APVLQQDLEQ 70 80 90 100 110 120 RLNCLCSFLQ RYCQTGSSAQ NLVQWQKILQ GENLEVELSK VIVILFYYST MSSKNPRKSE 130 140 150 160 170 180 DIDHKTQTEL ASILRFVLDN EDALCLDDKL INFLKRKAPF PSSGNDPSSS SDAMTPNVSH 190 200 210 220 230 240 RRKSEVRFLQ LHSVASSSTV KSLSADAPSS PMIEVLHTPQ FQMRRLKKQL SEVRECRDEL 250 260 270 280 290 300 EVELAENRKH LAEKEAQISL LQQQIENLRI LRENQTELQE PKELEELREK NESLMIRLRD 310 320 330 340 350 360 TLKQCQDMKA DKKLLERKND QLAEENGELS YKVRDLSNRL AQLQEALYET TEEQELSLSN 370 380 390 400 410 420 WQQKQNQLES ELSGAVGEKK YLEEHNLILQ GKISMLEDQL KEMGEIDMPE TGDCMGDILK 430 440 450 460 470 480 LDDLKQELAV LNTQCLSLKE QIHQMEEEKS TAEVEMEAQK SRFESEKGQL QEIVTNLQTS 490 500 510 520 530 540 LSEITFQKER LDNEARAQQE HLMCQITTLK LEISKLKSSL VHKDEELKGI HHKVEEERNE 550 560 570 580 590 600 KNQLLENFKM LGGNLIGITQ QLESKTKEVD YLREQQQKIL CERDSTLSTL NEYKCKKDEN 610 620 630 640 650 660 SGVLNKTVKT LEQDHQTSLS VIEKLKSEKE ELASKVQDLD AKMLGLIAKC QNLDSENDSQ 670 680 690 700 710 720 SKSHAATVES LKAQLSEQES QLKIYRKKVS SNELVSEENS KLKDQLLSVE ESLRHLREHL 730 740 750 760 770 780 EKEKTKFAAS LDADLKRISH LEEEMKKLSE SRDEALHNLD EERTAGKKIE SQLKHLEEEY 790 800 810 820 830 840 QKANESLQAK LAGSCAAIKQ REEERDELSK VVDIWKAKYG ESQQKIAQNS CHMQEQTEEL 850 860 870 880 890 900 KKTHSDVYQQ LEGERSKVLM IEAKASETKS SQLEKINQLE GELSAANACI KEREAEEKKL 910 920 930 940 950 960 VSALHSAEEK LKIAYQGESE RLSHLETALS NAKQDLDCLA KELSDEKYKK AEFEAMVKVL 970 980 990 1000 1010 1020 KEQNSERIAS LESELKNSLA VVKERKCESE KLSGEVEHLK RQLDDSSQKH KEALAQKNIE 1030 1040 1050 1060 1070 1080 IKQLINAKEK ATSDLAIKSE MGAQLQKAVD THKSEFSALQ NELSRSLDLL ALKEGEVERL 1090 1100 1110 1120 1130 1140 NKEAALRQEE IQQQQQTITK LTEEETALAA LKDKVALQEK EIKQQVQATK GAEKEMAKLK 1150 1160 1170 1180 1190 1200 SVISEKSKRI ECLEQDIQNQ KRDLSCIQEQ HQSKLGESQG LQALIADLEK KCKEQKELIC 1210 1220 1230 1240 1250 1260 EAQNKAAEAK TLASEKASVS ERQLEGIQAL EIEIGKERQK ACDLQKQLEL SWAVQEEKET 1270 1280 1290 1300 1310 1320 ELQALKKELF HKVQELEQSQ TSFTDSSGEA LLYLSEAQER QQALTEAKEQ AEQYQKEIEM 1330 1340 1350 1360 1370 1380 KNKEVNSLQA EIKILSSKVT TNEEVSVDFE QRLLKETSKS AKLEEKMQKL HMELEASFKE 1390 1400 1410 1420 1430 1440 LLEKNCAIDC LTTEAQNLKG EADQQRMAVD SLQQKLSSKA ETNHTLQQEI QAWQKNCAEK 1450 1460 1470 1480 1490 1500 EQQICSLQQN LKSNQSLLEE FASLKHSYQE IIAERDLMQE KHQEELLSHK KLTERFQAEL 1510 1520 1530 1540 1550 1560 EKAKEDMTEI VLLKEKLHNQ ELQLHKFQSE NSYSLTQISH LQQVNSQLLG ANQSLSQISD 1570 1580 1590 1600 1610 1620 QGAKKLESEM STLKEQHKEE MKTLRLQYEK TLREGNKQVQ ETSLQLETVT SKYDHVKSKV 1630 1640 1650 1660 1670 1680 LKDQKTFQEE KQRLLLQVQE LNKQLSQQEK TIRSQQQKLK QREGETHEEA DKSHKRVLEL 1690 1700 1710 1720 1730 1740 ESQLEQQTQA VEHYKAQMEK AKVHYDAKKK QNQELSEELQ SHIKQQEHLS KENADLKAES 1750 1760 1770 1780 1790 1800 EQLHKELQHS LLQSKEVEQN CKNLSNRVRS LEASWSTLTG QLRDPGKFQL ATAFHEESGH 1810 1820 1830 1840 1850 1860 FCAPRQTRSH ADVSIDSLDL SFGEDQLLNS TSERCNEEPA TSSVHASSPD SLISGQLPKK 1870 1880 1890 1900 1910 1920 VESLESLYFT PIPTRAQSKL ESSIGSIGDL SLDSSKKTQS ARRRTMQIIN ITMTKKTKEE 1930 1940 1950 1960 1970 1980 PESANTSFYS LRSAPSYQSL HLQNPRRAGR PPAAISAPAL ASLPSQESLA KTEHFSSDDS 1990 2000 2010 2020 2030 2040 LNNLPGYQHP TRRSARLSQT GGRSSFYMST CQDEPDPQDD WTRIAELQAR NKTCPPHLKT 2050 2060 2070 2080 2090 2100 SYPLESRPSI FSSTITDEEV KLGDPKETLR RATLLPGQIQ DSMTSTRRQT LAVPGAEHLK 2110 2120 2130 2140 2150 2160 GHNISTRQQM KRVSEESHYG PDTPEAKKTA TCFPRPMTPK DKHDTRRVST MESKGSSSHQ 2170 2180 2190 2200 2210 2220 QAQPTRRQAT AFSIFNTPKK LGNSLLKRGL NKKTTPKNSP RGRGANGSTS STSNKPSHLS 2230 2240 2250 LRKSPSQRSP RVSTAKSPRA SNKLFERKQQ RNK

References

[1]	"A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly." Merdes A., Ramyar K., Vechio J.D., Cleveland D.W. Cell 87:447-458(1996) [PubMed: 8898198] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y07624 mRNA. Translation: CAA68905.1.
PIR	T30336.
RefSeq	NP_001081559.1. NM_001088090.1.
UniGene	Xl.1261.
3D structure databases
ProteinModelPortal	P70012.
ModBase	Search...
Protein-protein interaction databases
IntAct	P70012. 3 interactions.
MINT	MINT-189361.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	397920.
KEGG	xla:397920.
Organism-specific databases
CTD	397920.
Xenbase	XB-GENE-6252170. numa1.
Phylogenomic databases
HOVERGEN	HBG052694.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

P70012_XENLA

Accession

Primary (citable) accession number: P70012

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 1997
Last sequence update:	February 1, 1997
Last modified:	October 19, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)