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P70006 (P70006_XENLA) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Hepatocyte growth factor-like protein EMBL CAA69989.1
Gene names
Name:mst1 Xenbase XB-GENE-865755
OrganismXenopus laevis (African clawed frog) EMBL CAA69989.1
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length717 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Contains 1 peptidase S1 domain. SAAS SAAS018056

Ontologies

Keywords
   DomainKringle SAAS SAAS018056
Signal EMBL CAA69989.1
   PTMDisulfide bond SAAS SAAS018056
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: InterPro

   Molecular_functionserine-type endopeptidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Potential EMBL CAA69989.1
Chain29 – 717689hepatocyte growth factor-like protein EMBL CAA69989.1
PRO_5000146962
Chain30 – 717688 Potential EMBL CAA69989.1
PRO_5000146961

Sequences

Sequence LengthMass (Da)Tools
P70006 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 6F877A432C8CDD54

FASTA71782,018
        10         20         30         40         50         60 
MRHITVPSNM KSCLFLLCFN AAVFFVTGTA HRSALNDYQR SKGLELVHMN EGGVKQEVQA 

        70         80         90        100        110        120 
EIQICAKQCS DLLDCRSFDY NWKSQSCRLL PWTQNSSNVL LQRNVQYDLY QKKDYIRDCV 

       130        140        150        160        170        180 
VGNGNTYRGT VSKTKNGRTC QHWRLKFPHD HKFSPTHWPE LEENYCRNPD SDPEGLWCYT 

       190        200        210        220        230        240 
TDKNIRHQYC GIKKCEDAVC LTCNGEDYRG SVDRTESGKE CQRWDLQAPH THPYKPEKYP 

       250        260        270        280        290        300 
DKSLDDNYCR NPDSSERPWC YTTDPNVERE FCHITKCKKQ RISNIEITST CFKERGEGYR 

       310        320        330        340        350        360 
GKANTTTSGI PCQRWDTQAP HVHRFLPEKY PCKGLDENYC RNPVGSEAPW CFTTLKNMRM 

       370        380        390        400        410        420 
AYCFQIKRCT DDVVEPECYH GNGELYRGRV SKTRKGIMCR RWEEKQNDLE LSLAQPYLVP 

       430        440        450        460        470        480 
LEENYCRNPD RDSHGPWCYT MDPNTPFDYC ALKPCAGDKV LTLEEAESIA FDSCGKRTDR 

       490        500        510        520        530        540 
LLRKSRIVGG EPGNSPWTVS LRNRQGEHFC GGSLVKENWV ISTRQCFSSC DADLSGYEAV 

       550        560        570        580        590        600 
MGTLFKNPSP DDPDRQSVPI SKIVCGPSDS SLVMLKLQWP VTLNSRVALI CLPPERYIVP 

       610        620        630        640        650        660 
EDTKCEIAGW GDTQGTGHDN VLKIASFYIL SNDNCNKNYR SQRNKVLDNE MCTKPMTVDV 

       670        680        690        700        710 
GACEGDYGGP LACLTHDCWV LEGVIVPARG CGKKNQPAIF TRVSVYVDWI NKVMKMV

« Hide

References

[1]"The Xenopus homologue of hepatocyte growth factor-like protein is specifically expressed in the presumptive neural plate during gastrulation."
Aberger F., Schmidt G., Richter K.
Mech. Dev. 54:23-37(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Kidney EMBL CAA69989.1 and Liver EMBL CAA69989.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Y08734 mRNA. Translation: CAA69989.1.
RefSeqNP_001079527.1. NM_001086058.1.
UniGeneXl.216.

3D structure databases

HSSPHSSP built from PDB template 1FDP based on UniProtKB P00746.
ProteinModelPortalP70006.
SMRP70006. Positions 487-714.
ModBaseSearch...

Protein family/group databases

MEROPSS01.977.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID379214.
KEGGxla:379214.

Organism-specific databases

CTD4485.
XenbaseXB-GENE-865755. mst1.

Phylogenomic databases

HOVERGENHBG004381.

Family and domain databases

Gene3D2.40.20.10. 4 hits.
InterProIPR024174. HGF_MST1.
IPR000001. Kringle.
IPR013806. Kringle-like.
IPR018056. Kringle_CS.
IPR003014. PAN-1_domain.
IPR003609. Pan_app.
IPR001254. Peptidase_S1.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamPF00051. Kringle. 4 hits.
PF00024. PAN_1. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view]
PIRSFPIRSF001152. HGF_MST1. 1 hit.
PRINTSPR00722. CHYMOTRYPSIN.
SMARTSM00130. KR. 4 hits.
SM00473. PAN_AP. 1 hit.
SM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMSSF57440. Kringle-like. 4 hits.
SSF50494. Pept_Ser_Cys. 1 hit.
PROSITEPS00021. KRINGLE_1. 4 hits.
PS50070. KRINGLE_2. 4 hits.
PS50948. PAN. 1 hit.
PS50240. TRYPSIN_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP70006_XENLA
AccessionPrimary (citable) accession number: P70006
Entry history
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: April 3, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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