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P69687 (CAPSD_TMV) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Capsid protein
Alternative name(s):
Coat protein
Gene names
Name:CP
OrganismTobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1)) [Reference proteome]
Taxonomic identifier12243 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageVirgaviridaeTobamovirus
Virus hostNicotiana tabacum (Common tobacco) [TaxID: 4097]

Protein attributes

Sequence length159 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.

Subcellular location

Virion Potential.

Sequence similarities

Belongs to the virgaviridae capsid protein family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed; by host Ref.3 Ref.4 Ref.5
Chain2 – 159158Capsid protein
PRO_0000144918

Amino acid modifications

Modified residue21N-acetylserine; by host

Natural variations

Natural variant291T → I in PM2; DT1 and DT2.
Natural variant791P → S in DT2.
Natural variant961E → D in PM2; DT1 and DT2.
Natural variant1041T → M in PM2.
Natural variant1381G → R in DT1 and DT2.
Natural variant1491S → Y in DT2.

Secondary structure

.................... 159
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P69687 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 5C90E8478A43DBC4

FASTA15917,624
        10         20         30         40         50         60 
MSYSITTPSQ FVFLSSAWAD PIELINLCTN ALGNQFQTQQ ARTVVQRQFS EVWKPSPQVT 

        70         80         90        100        110        120 
VRFPDSDFKV YRYNAVLDPL VTALLGAFDT RNRIIEVENQ ANPTTAETLD ATRRVDDATV 

       130        140        150 
AIRSAINNLI VELIRGTGSY NRSSFESSSG LVWTSGPAT 

« Hide

References

[1]"Nucleotide sequence of tobacco mosaic virus RNA."
Goelet P., Lomonossoff G.P., Butler P.J.G., Akam M.E., Gait M.J., Karn J.
Proc. Natl. Acad. Sci. U.S.A. 79:5818-5822(1982) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"Sequence of 1000 nucleotides at the 3' end of tobacco mosaic virus RNA."
Guilley H., Jonard G., Kukla B., Richards K.E.
Nucleic Acids Res. 6:1287-1308(1979) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[3]"The complete amino acid sequence of the protein of tobacco mosaic virus."
Tsugita A., Gish D.T., Young J., Fraenkel-Conrat H., Knight C.A., Stanley W.M.
Proc. Natl. Acad. Sci. U.S.A. 46:1463-1469(1960) [PubMed] [Europe PMC] [Abstract]
Cited for: PRELIMINARY PROTEIN SEQUENCE OF 2-159.
[4]"Studies on the amino acid sequence of tobacco mosaic virus protein. V. Amino acid sequences of two peptides from tryptic digests and location of amide group."
Funatsu G., Tsugita A., Fraenkel-Conrat H.
Arch. Biochem. Biophys. 105:25-41(1964) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-42 AND 94-113, SEQUENCE REVISION.
[5]"The sequence of amino acids in the protein of tobacco mosaic virus. IV. Separation of tobacco mosaic virus protein with trypsin."
Anderer F.A., Handschuh D.
Z. Naturforsch. B 17:536-543(1962)
Cited for: PROTEIN SEQUENCE OF 2-159.
[6]"Further studies on amino acid sequence of proteins in tobacco mosaic virus."
Anderer F.A., Wittmann-Liebold B., Wittmann H.G.
Z. Naturforsch. B 20:1203-1213(1965) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.
[7]"Amino acid sequences of some common Japanese strains of tobacco mosaic virus."
Nozu Y., Ohno T., Okada Y.
J. Biochem. 68:39-52(1970) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.
[8]"Capsid protein gene sequences of four tobacco mosaic virus strains defective for virus assembly."
Kuhlmann U., Sarkar S., Rohde W.
Nucleic Acids Res. 21:3325-3325(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: MUTANTS DEFECTIVE CAPSID PM2; DT1 AND DT2.
[9]"Structure of tobacco mosaic virus at 3.6-A resolution: implications for assembly."
Namba K., Stubbs G.
Science 231:1401-1406(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.6 ANGSTROMS) OF 1-159.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
V01408 Unassigned RNA. No translation available.
V01409 Genomic RNA. No translation available.
V01406 Genomic RNA. Translation: CAA24685.1.
X70882 mRNA. Translation: CAA50227.1.
X70883 mRNA. Translation: CAA50228.1.
X70884 mRNA. Translation: CAA50229.1.
RefSeqNP_597750.1. NC_001367.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1EI7X-ray2.45A/B2-159[»]
2TMVfiber diffraction2.90P2-159[»]
3J06electron microscopy-A1-159[»]
3KMLX-ray3.01A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q2-100[»]
4GQHX-ray3.06A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d/e/f/h/i2-155[»]
ProteinModelPortalP69687.
SMRP69687. Positions 2-159.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-59677N.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1494080.

Family and domain databases

Gene3D1.20.120.70. 1 hit.
InterProIPR001337. TMV-like_coat.
[Graphical view]
PfamPF00721. TMV_coat. 1 hit.
[Graphical view]
SUPFAMSSF47195. SSF47195. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP69687.

Entry information

Entry nameCAPSD_TMV
AccessionPrimary (citable) accession number: P69687
Secondary accession number(s): P03570
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references