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Protein

Citrate lyase acyl carrier protein

Gene

citD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Covalent carrier of the coenzyme of citrate lyase.

GO - Molecular functioni

  • prosthetic group binding Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:ACPSUB-MONOMER.
ECOL316407:JW0609-MONOMER.
MetaCyc:ACPSUB-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate lyase acyl carrier protein
Alternative name(s):
Citrate lyase gamma chain
Gene namesi
Name:citD
Synonyms:ybdX
Ordered Locus Names:b0617, JW0609
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13543. citD.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9898Citrate lyase acyl carrier proteinPRO_0000214695Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei14 – 141O-(phosphoribosyl dephospho-coenzyme A)serineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP69330.

Expressioni

Inductioni

Repressed by H-NS. Part of the citCDEFXG operon.1 Publication

Interactioni

Subunit structurei

Oligomer with a subunit composition of (alpha,beta, gamma)6.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
glpDP130351EBI-1119230,EBI-548509

Protein-protein interaction databases

BioGridi4259652. 9 interactions.
IntActiP69330. 3 interactions.
STRINGi511145.b0617.

Structurei

3D structure databases

ProteinModelPortaliP69330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CitD family.Curated

Phylogenomic databases

eggNOGiENOG4105XGS. Bacteria.
COG3052. LUCA.
HOGENOMiHOG000040480.
InParanoidiP69330.
KOiK01646.
OMAiYNWKEID.
OrthoDBiEOG6S52TW.
PhylomeDBiP69330.

Family and domain databases

HAMAPiMF_00805. CitD.
InterProiIPR006495. CitD.
IPR023439. Mal_deCO2ase/Cit_lyase_ACP.
[Graphical view]
PfamiPF06857. ACP. 1 hit.
[Graphical view]
PIRSFiPIRSF002736. Citrt_lyas_gamma. 1 hit.
ProDomiPD015389. CitD. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01608. citD. 1 hit.

Sequencei

Sequence statusi: Complete.

P69330-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKINQPAVAG TLESGDVMIR IAPLDTQDID LQINSSVEKQ FGDAIRTTIL
60 70 80 90
DVLARYNVRG VQLNVDDKGA LDCILRARLE ALLARASGIP ALPWEDCQ
Length:98
Mass (Da):10,689
Last modified:February 15, 2005 - v1
Checksum:i5932A2109978398A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti93 – 986PWEDCQ → HGRIANDFRFAATT (PubMed:8905232).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U46667 Genomic DNA. Translation: AAC28949.1.
U82598 Genomic DNA. Translation: AAB40817.1.
U00096 Genomic DNA. Translation: AAC73718.1.
AP009048 Genomic DNA. Translation: BAA35253.1.
PIRiG64795.
RefSeqiNP_415150.1. NC_000913.3.
WP_000700703.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73718; AAC73718; b0617.
BAA35253; BAA35253; BAA35253.
GeneIDi945415.
KEGGiecj:JW0609.
eco:b0617.
PATRICi32116414. VBIEscCol129921_0647.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U46667 Genomic DNA. Translation: AAC28949.1.
U82598 Genomic DNA. Translation: AAB40817.1.
U00096 Genomic DNA. Translation: AAC73718.1.
AP009048 Genomic DNA. Translation: BAA35253.1.
PIRiG64795.
RefSeqiNP_415150.1. NC_000913.3.
WP_000700703.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP69330.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259652. 9 interactions.
IntActiP69330. 3 interactions.
STRINGi511145.b0617.

Proteomic databases

PaxDbiP69330.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73718; AAC73718; b0617.
BAA35253; BAA35253; BAA35253.
GeneIDi945415.
KEGGiecj:JW0609.
eco:b0617.
PATRICi32116414. VBIEscCol129921_0647.

Organism-specific databases

EchoBASEiEB3313.
EcoGeneiEG13543. citD.

Phylogenomic databases

eggNOGiENOG4105XGS. Bacteria.
COG3052. LUCA.
HOGENOMiHOG000040480.
InParanoidiP69330.
KOiK01646.
OMAiYNWKEID.
OrthoDBiEOG6S52TW.
PhylomeDBiP69330.

Enzyme and pathway databases

BioCyciEcoCyc:ACPSUB-MONOMER.
ECOL316407:JW0609-MONOMER.
MetaCyc:ACPSUB-MONOMER.

Miscellaneous databases

PROiP69330.

Family and domain databases

HAMAPiMF_00805. CitD.
InterProiIPR006495. CitD.
IPR023439. Mal_deCO2ase/Cit_lyase_ACP.
[Graphical view]
PfamiPF06857. ACP. 1 hit.
[Graphical view]
PIRSFiPIRSF002736. Citrt_lyas_gamma. 1 hit.
ProDomiPD015389. CitD. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01608. citD. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Ingmer H., Cohen S.N.
    Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  5. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. "Involvement of the leucine response transcription factor LeuO in regulation of the genes for sulfa drug efflux."
    Shimada T., Yamamoto K., Ishihama A.
    J. Bacteriol. 191:4562-4571(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: OPERON STRUCTURE, INDUCTION.
    Strain: K12 / BW25113.

Entry informationi

Entry nameiCITD_ECOLI
AccessioniPrimary (citable) accession number: P69330
Secondary accession number(s): O54336, P77618
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: January 20, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.