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P69216

- COX3_BRAFL

UniProt

P69216 - COX3_BRAFL

Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
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    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:COIII
    Encoded oniMitochondrion
    OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)
    Taxonomic identifieri7739 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
    ProteomesiUP000001554: Mitochondrion

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 262262Cytochrome c oxidase subunit 3PRO_0000183747Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP69216.
    SMRiP69216. Positions 4-262.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei11 – 3121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei32 – 5221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei83 – 10321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei125 – 14723HelicalSequence AnalysisAdd
    BLAST
    Transmembranei160 – 18021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei198 – 21821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei240 – 26021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOVERGENiHBG016686.
    KOiK02262.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P69216-1 [UniParc]FASTAAdd to Basket

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    MTGYQPHPWH LVEPSPWPLV GGSAAFTLTV GLVMWFHYNS ISLMILGLVM    50
    IVATMIQWWR DVIREATFQG CHTSYVLSGL RRGMVLFIVS EVFFFLAFFW 100
    AFFHSSLAPT VELGVTWPPV GVHPLNAFAV PLLNTAVLLS SGVTVTWAHH 150
    ALMEGKRTEA IQSLAITVML GLYFTGLQAW EYYEAPFTIA DSVYGSTFFV 200
    ATGFHGLHVI IGSTFLMVCL GRQVFYHYTS SHHFGFEAAA WYWHFVDVVW 250
    LFLYVCIYWW GS 262
    Length:262
    Mass (Da):29,711
    Last modified:February 15, 2005 - v1
    Checksum:i6D93D8338AC870D8
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti6 – 61P → S in strain: Bf-H09. 1 Publication
    Natural varianti52 – 521V → I in strain: Bf-M01 and Bf-H10. 1 Publication
    Natural varianti160 – 1601A → V in strain: Bf-H07. 1 Publication
    Natural varianti210 – 2101I → V in strain: Bf-H03 and Bf-H04. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB478574 Genomic DNA. Translation: BAH86333.1.
    AB478575 Genomic DNA. Translation: BAH86346.1.
    AB478576 Genomic DNA. Translation: BAH86359.1.
    AB478577 Genomic DNA. Translation: BAH86372.1.
    AB478578 Genomic DNA. Translation: BAH86385.1.
    AB478579 Genomic DNA. Translation: BAH86398.1.
    AB478580 Genomic DNA. Translation: BAH86411.1.
    AB478581 Genomic DNA. Translation: BAH86424.1.
    AB478582 Genomic DNA. Translation: BAH86437.1.
    AB478583 Genomic DNA. Translation: BAH86450.1.
    AB478584 Genomic DNA. Translation: BAH86463.1.
    AB478585 Genomic DNA. Translation: BAH86476.1.
    AB478586 Genomic DNA. Translation: BAH86489.1.
    AB478587 Genomic DNA. Translation: BAH86502.1.
    AB478588 Genomic DNA. Translation: BAH86515.1.
    AB478589 Genomic DNA. Translation: BAH86528.1.
    AB478590 Genomic DNA. Translation: BAH86541.1.
    AB478591 Genomic DNA. Translation: BAH86554.1.
    AB478592 Genomic DNA. Translation: BAH86567.1.
    AB478593 Genomic DNA. Translation: BAH86580.1.
    AF098298 Genomic DNA. Translation: AAB87994.1.
    RefSeqiNP_007761.1. NC_000834.1.

    Genome annotation databases

    GeneIDi808730.
    KEGGibfo:COX3.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB478574 Genomic DNA. Translation: BAH86333.1 .
    AB478575 Genomic DNA. Translation: BAH86346.1 .
    AB478576 Genomic DNA. Translation: BAH86359.1 .
    AB478577 Genomic DNA. Translation: BAH86372.1 .
    AB478578 Genomic DNA. Translation: BAH86385.1 .
    AB478579 Genomic DNA. Translation: BAH86398.1 .
    AB478580 Genomic DNA. Translation: BAH86411.1 .
    AB478581 Genomic DNA. Translation: BAH86424.1 .
    AB478582 Genomic DNA. Translation: BAH86437.1 .
    AB478583 Genomic DNA. Translation: BAH86450.1 .
    AB478584 Genomic DNA. Translation: BAH86463.1 .
    AB478585 Genomic DNA. Translation: BAH86476.1 .
    AB478586 Genomic DNA. Translation: BAH86489.1 .
    AB478587 Genomic DNA. Translation: BAH86502.1 .
    AB478588 Genomic DNA. Translation: BAH86515.1 .
    AB478589 Genomic DNA. Translation: BAH86528.1 .
    AB478590 Genomic DNA. Translation: BAH86541.1 .
    AB478591 Genomic DNA. Translation: BAH86554.1 .
    AB478592 Genomic DNA. Translation: BAH86567.1 .
    AB478593 Genomic DNA. Translation: BAH86580.1 .
    AF098298 Genomic DNA. Translation: AAB87994.1 .
    RefSeqi NP_007761.1. NC_000834.1.

    3D structure databases

    ProteinModelPortali P69216.
    SMRi P69216. Positions 4-262.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 808730.
    KEGGi bfo:COX3.

    Organism-specific databases

    CTDi 4514.

    Phylogenomic databases

    HOVERGENi HBG016686.
    KOi K02262.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Branchiostoma mitochondrial DNA, complete genome."
      Takada Y., Imai T.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS SER-6; ILE-52; VAL-160 AND VAL-210.
      Strain: Bf-H01, Bf-H02, Bf-H03, Bf-H04, Bf-H05, Bf-H06, Bf-H07, Bf-H08, Bf-H09, Bf-H10, Bf-M01, Bf-M02, Bf-M03, Bf-M04, Bf-M05, Bf-M06, Bf-M07, Bf-M08, Bf-M09 and Bf-M10.
    2. "Complete sequence, gene arrangement, and genetic code of mitochondrial DNA of the cephalochordate Branchiostoma floridae (Amphioxus)."
      Boore J.L., Daehler L.L., Brown W.M.
      Mol. Biol. Evol. 16:410-418(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCOX3_BRAFL
    AccessioniPrimary (citable) accession number: P69216
    Secondary accession number(s): C6L3C4
    , C6L3D7, C6L3L5, C6L3Q4, C6L3Z5, C6L408, O47425
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 15, 2005
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3