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P69216

- COX3_BRAFL

UniProt

P69216 - COX3_BRAFL

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Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
ProteomesiUP000001554: Mitochondrion

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262Cytochrome c oxidase subunit 3PRO_0000183747Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP69216.
SMRiP69216. Positions 4-262.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei11 – 3121HelicalSequence AnalysisAdd
BLAST
Transmembranei32 – 5221HelicalSequence AnalysisAdd
BLAST
Transmembranei83 – 10321HelicalSequence AnalysisAdd
BLAST
Transmembranei125 – 14723HelicalSequence AnalysisAdd
BLAST
Transmembranei160 – 18021HelicalSequence AnalysisAdd
BLAST
Transmembranei198 – 21821HelicalSequence AnalysisAdd
BLAST
Transmembranei240 – 26021HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG016686.
InParanoidiP69216.
KOiK02262.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P69216 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTGYQPHPWH LVEPSPWPLV GGSAAFTLTV GLVMWFHYNS ISLMILGLVM
60 70 80 90 100
IVATMIQWWR DVIREATFQG CHTSYVLSGL RRGMVLFIVS EVFFFLAFFW
110 120 130 140 150
AFFHSSLAPT VELGVTWPPV GVHPLNAFAV PLLNTAVLLS SGVTVTWAHH
160 170 180 190 200
ALMEGKRTEA IQSLAITVML GLYFTGLQAW EYYEAPFTIA DSVYGSTFFV
210 220 230 240 250
ATGFHGLHVI IGSTFLMVCL GRQVFYHYTS SHHFGFEAAA WYWHFVDVVW
260
LFLYVCIYWW GS
Length:262
Mass (Da):29,711
Last modified:February 15, 2005 - v1
Checksum:i6D93D8338AC870D8
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti6 – 61P → S in strain: Bf-H09. 1 Publication
Natural varianti52 – 521V → I in strain: Bf-M01 and Bf-H10. 1 Publication
Natural varianti160 – 1601A → V in strain: Bf-H07. 1 Publication
Natural varianti210 – 2101I → V in strain: Bf-H03 and Bf-H04. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB478574 Genomic DNA. Translation: BAH86333.1.
AB478575 Genomic DNA. Translation: BAH86346.1.
AB478576 Genomic DNA. Translation: BAH86359.1.
AB478577 Genomic DNA. Translation: BAH86372.1.
AB478578 Genomic DNA. Translation: BAH86385.1.
AB478579 Genomic DNA. Translation: BAH86398.1.
AB478580 Genomic DNA. Translation: BAH86411.1.
AB478581 Genomic DNA. Translation: BAH86424.1.
AB478582 Genomic DNA. Translation: BAH86437.1.
AB478583 Genomic DNA. Translation: BAH86450.1.
AB478584 Genomic DNA. Translation: BAH86463.1.
AB478585 Genomic DNA. Translation: BAH86476.1.
AB478586 Genomic DNA. Translation: BAH86489.1.
AB478587 Genomic DNA. Translation: BAH86502.1.
AB478588 Genomic DNA. Translation: BAH86515.1.
AB478589 Genomic DNA. Translation: BAH86528.1.
AB478590 Genomic DNA. Translation: BAH86541.1.
AB478591 Genomic DNA. Translation: BAH86554.1.
AB478592 Genomic DNA. Translation: BAH86567.1.
AB478593 Genomic DNA. Translation: BAH86580.1.
AF098298 Genomic DNA. Translation: AAB87994.1.
RefSeqiNP_007761.1. NC_000834.1.

Genome annotation databases

GeneIDi808730.
KEGGibfo:COX3.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB478574 Genomic DNA. Translation: BAH86333.1 .
AB478575 Genomic DNA. Translation: BAH86346.1 .
AB478576 Genomic DNA. Translation: BAH86359.1 .
AB478577 Genomic DNA. Translation: BAH86372.1 .
AB478578 Genomic DNA. Translation: BAH86385.1 .
AB478579 Genomic DNA. Translation: BAH86398.1 .
AB478580 Genomic DNA. Translation: BAH86411.1 .
AB478581 Genomic DNA. Translation: BAH86424.1 .
AB478582 Genomic DNA. Translation: BAH86437.1 .
AB478583 Genomic DNA. Translation: BAH86450.1 .
AB478584 Genomic DNA. Translation: BAH86463.1 .
AB478585 Genomic DNA. Translation: BAH86476.1 .
AB478586 Genomic DNA. Translation: BAH86489.1 .
AB478587 Genomic DNA. Translation: BAH86502.1 .
AB478588 Genomic DNA. Translation: BAH86515.1 .
AB478589 Genomic DNA. Translation: BAH86528.1 .
AB478590 Genomic DNA. Translation: BAH86541.1 .
AB478591 Genomic DNA. Translation: BAH86554.1 .
AB478592 Genomic DNA. Translation: BAH86567.1 .
AB478593 Genomic DNA. Translation: BAH86580.1 .
AF098298 Genomic DNA. Translation: AAB87994.1 .
RefSeqi NP_007761.1. NC_000834.1.

3D structure databases

ProteinModelPortali P69216.
SMRi P69216. Positions 4-262.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 808730.
KEGGi bfo:COX3.

Organism-specific databases

CTDi 4514.

Phylogenomic databases

HOVERGENi HBG016686.
InParanoidi P69216.
KOi K02262.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Branchiostoma mitochondrial DNA, complete genome."
    Takada Y., Imai T.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS SER-6; ILE-52; VAL-160 AND VAL-210.
    Strain: Bf-H01, Bf-H02, Bf-H03, Bf-H04, Bf-H05, Bf-H06, Bf-H07, Bf-H08, Bf-H09, Bf-H10, Bf-M01, Bf-M02, Bf-M03, Bf-M04, Bf-M05, Bf-M06, Bf-M07, Bf-M08, Bf-M09 and Bf-M10.
  2. "Complete sequence, gene arrangement, and genetic code of mitochondrial DNA of the cephalochordate Branchiostoma floridae (Amphioxus)."
    Boore J.L., Daehler L.L., Brown W.M.
    Mol. Biol. Evol. 16:410-418(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCOX3_BRAFL
AccessioniPrimary (citable) accession number: P69216
Secondary accession number(s): C6L3C4
, C6L3D7, C6L3L5, C6L3Q4, C6L3Z5, C6L408, O47425
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3