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P69215 (COX3_BRALA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismBranchiostoma lanceolatum (Common lancelet) (Amphioxus)
Taxonomic identifier7740 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262Cytochrome c oxidase subunit 3
PRO_0000183748

Regions

Transmembrane11 – 3121Helical; Potential
Transmembrane32 – 5221Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane125 – 14723Helical; Potential
Transmembrane160 – 18021Helical; Potential
Transmembrane198 – 21821Helical; Potential
Transmembrane240 – 26021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P69215 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 6D93D8338AC870D8

FASTA26229,711
        10         20         30         40         50         60 
MTGYQPHPWH LVEPSPWPLV GGSAAFTLTV GLVMWFHYNS ISLMILGLVM IVATMIQWWR 

        70         80         90        100        110        120 
DVIREATFQG CHTSYVLSGL RRGMVLFIVS EVFFFLAFFW AFFHSSLAPT VELGVTWPPV 

       130        140        150        160        170        180 
GVHPLNAFAV PLLNTAVLLS SGVTVTWAHH ALMEGKRTEA IQSLAITVML GLYFTGLQAW 

       190        200        210        220        230        240 
EYYEAPFTIA DSVYGSTFFV ATGFHGLHVI IGSTFLMVCL GRQVFYHYTS SHHFGFEAAA 

       250        260 
WYWHFVDVVW LFLYVCIYWW GS 

« Hide

References

[1]"Complete sequence of the amphioxus (Branchiostoma lanceolatum) mitochondrial genome: relations to vertebrates."
Spruyt N., Delarbre C., Gachelin G., Laudet V.
Nucleic Acids Res. 26:3279-3285(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y16474 Genomic DNA. Translation: CAA76253.1.
PIRH71390.
RefSeqNP_007543.1. NC_001912.1.

3D structure databases

ProteinModelPortalP69215.
SMRP69215. Positions 4-262.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808215.

Organism-specific databases

CTD4514.

Phylogenomic databases

HOVERGENHBG016686.
ProtClustDBMTH00189.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_BRALA
AccessionPrimary (citable) accession number: P69215
Secondary accession number(s): O47425
Entry history
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families