P69153 (MT23A_MYTED) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Metallothionein 20-III isoform A Short name=MT-20-IIIA
Organism	Mytilus edulis (Blue mussel)
Taxonomic identifier	6550 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Bivalvia › Pteriomorphia › Mytiloida › Mytiloidea › Mytilidae › Mytilinae › Mytilus

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	The metallothioneins are involved in the cellular sequestration of toxic metal ions.
Subunit structure	Homodimer.
Induction	By cadmium.
Sequence similarities	Belongs to the metallothionein superfamily. Type 2 family.

Ontologies

Keywords
Ligand	Cadmium Metal-binding Metal-thiolate cluster
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.1
	Chain	2 – 72	71	Metallothionein 20-III isoform A		PRO_0000197331

Sequences

	Sequence		Length	Mass (Da)
	P69153 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 12868683A0857631	FASTA	72	7,030
	10 20 30 40 50 60 MPGPCNCIET NVCICGTGCS GKCCQCGDAC KCASGCGCSG CKVVCRCSGT CACGCDCTGP 70 INCKCESGCS CK

References

[1]

"Complete amino acid sequences of five dimeric and four monomeric forms of metallothionein from the edible mussel Mytilus edulis." Mackay E.A., Overnell J., Dunbar B., Davidson I., Hunziker P.E., Kaegi J.H.R., Fothergill J.E. Eur. J. Biochem. 218:183-194(1993) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-72.

Cross-references

Sequence databases
PIR	S39422.
3D structure databases
ProteinModelPortal	P69153.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001008. Metalthion_fam2_mollusc. IPR003019. Metalthion_sfam_euk. [Graphical view]
Pfam	PF00131. Metallothio. 1 hit. [Graphical view]
PRINTS	PR00875. MTMOLLUSC.
ProtoNet	Search...

Entry information

Entry name

MT23A_MYTED

Accession

Primary (citable) accession number: P69153
Secondary accession number(s): P80253, Q9GU31

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 21 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)