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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Staphylococcus aureus (strain N315)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecF
Gene namesi
Name:recF
Ordered Locus Names:SA0004
OrganismiStaphylococcus aureus (strain N315)
Taxonomic identifieri158879 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000751 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001964581 – 370DNA replication and repair protein RecFAdd BLAST370

Structurei

3D structure databases

ProteinModelPortaliP68862.
SMRiP68862.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.Curated

Phylogenomic databases

HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P68862-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNTLQLEN YRNYDEVTLK CHPDVNILIG ENAQGKTNLL ESIYTLALAK
60 70 80 90 100
SHRTSNDKEL IRFNADYAKI EGELSYRHGT MPLTMFITKK GKQVKVNHLE
110 120 130 140 150
QSRLTQYIGH LNVVLFAPED LNIVKGSPQI RRRFIDMELG QISAVYLNDL
160 170 180 190 200
AQYQRILKQK NNYLKQLQLG QKKDLTMLEV LNQQFAEYAM KVTDKRAHFI
210 220 230 240 250
QELESLAKPI HAGITNDKEA LSLNYLPSLK FDYAQNEAAR LEEIMSILSD
260 270 280 290 300
NMQREKERGI SLFGPHRDDI SFDVNGMDAQ TYGSQGQQRT TALSIKLAEI
310 320 330 340 350
ELMNIEVGEY PILLLDDVLS ELDDSRQTHL LSTIQHKVQT FVTTTSVDGI
360 370
DHEIMNNAKL YRINQGEIIK
Length:370
Mass (Da):42,415
Last modified:December 21, 2004 - v1
Checksum:i2D6471A9483B1368
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000018 Genomic DNA. Translation: BAB41220.1.
RefSeqiWP_000775113.1. NC_002745.2.

Genome annotation databases

EnsemblBacteriaiBAB41220; BAB41220; BAB41220.
GeneIDi28379635.
KEGGisau:SA0004.
PATRICi19572025. VBIStaAur116463_0004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000018 Genomic DNA. Translation: BAB41220.1.
RefSeqiWP_000775113.1. NC_002745.2.

3D structure databases

ProteinModelPortaliP68862.
SMRiP68862.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB41220; BAB41220; BAB41220.
GeneIDi28379635.
KEGGisau:SA0004.
PATRICi19572025. VBIStaAur116463_0004.

Phylogenomic databases

HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECF_STAAN
AccessioniPrimary (citable) accession number: P68862
Secondary accession number(s): P29232
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.