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Protein

Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C

Gene

gatC

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).By similarity

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.
ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C (EC:6.3.5.-)
Short name:
Asp/Glu-ADT subunit C
Gene namesi
Name:gatC
Ordered Locus Names:SAV1901
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001053301 – 100Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit CAdd BLAST100

Proteomic databases

PaxDbiP68807
PRIDEiP68807

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.By similarity

Protein-protein interaction databases

STRINGi158878.SAV1901

Structurei

Secondary structure

1100
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 15Combined sources10
Helixi22 – 39Combined sources18
Helixi40 – 44Combined sources5
Helixi74 – 78Combined sources5
Beta strandi82 – 85Combined sources4
Beta strandi88 – 92Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DF4X-ray3.20C1-100[»]
2DQNX-ray2.55C1-100[»]
2F2AX-ray2.30C1-100[»]
2G5HX-ray2.50C1-100[»]
2G5IX-ray3.35C1-100[»]
3IP4X-ray1.90C1-100[»]
ProteinModelPortaliP68807
SMRiP68807
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP68807

Family & Domainsi

Sequence similaritiesi

Belongs to the GatC family.Curated

Phylogenomic databases

eggNOGiENOG4105VB5 Bacteria
COG0721 LUCA
HOGENOMiHOG000017523
KOiK02435
OMAiPATSHPI
PhylomeDBiP68807

Family and domain databases

HAMAPiMF_00122 GatC, 1 hit
InterProiView protein in InterPro
IPR003837 Asp/Glu-ADT_csu
IPR036113 Asp/Glu-ADT_sf_sub_c
PANTHERiPTHR15004 PTHR15004, 1 hit
PfamiView protein in Pfam
PF02686 Glu-tRNAGln, 1 hit
SUPFAMiSSF141000 SSF141000, 1 hit
TIGRFAMsiTIGR00135 gatC, 1 hit

Sequencei

Sequence statusi: Complete.

P68807-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVTREEVE HIANLARLQI SPEETEEMAN TLESILDFAK QNDSADTEGV
60 70 80 90 100
EPTYHVLDLQ NVLREDKAIK GIPQELALKN AKETEDGQFK VPTIMNEEDA
Length:100
Mass (Da):11,268
Last modified:December 21, 2004 - v1
Checksum:i7E9273A6AA979250
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB58063.1
RefSeqiWP_000170162.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB58063; BAB58063; SAV1901
KEGGisav:SAV1901

Similar proteinsi

Entry informationi

Entry nameiGATC_STAAM
AccessioniPrimary (citable) accession number: P68807
Secondary accession number(s): Q9RF08
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: December 21, 2004
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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