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Protein

Putative nuclease YbcO

Gene

ybcO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Based on its fold and a conserved His residue, has been predicted to be a nuclease.1 Publication

Miscellaneous

Encoded by the cryptic lambdoid prophage DLP12.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi13ZincCombined sources1
Metal bindingi21ZincCombined sources1
Active sitei32Proton acceptor1 Publication1
Metal bindingi54ZincCombined sources1
Metal bindingi57ZincCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Nuclease
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciEcoCyc:G6305-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative nuclease YbcO (EC:3.1.-.-)
Gene namesi
Name:ybcO
Ordered Locus Names:b0549, JW0537
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13631 ybcO

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001686541 – 96Putative nuclease YbcOAdd BLAST96

Proteomic databases

PaxDbiP68661
PRIDEiP68661

Interactioni

Protein-protein interaction databases

BioGridi4261524, 160 interactors
IntActiP68661, 1 interactor
STRINGi316385.ECDH10B_0505

Structurei

Secondary structure

196
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni7 – 10Combined sources4
Turni18 – 20Combined sources3
Helixi25 – 27Combined sources3
Beta strandi29 – 32Combined sources4
Beta strandi47 – 53Combined sources7
Helixi55 – 61Combined sources7
Helixi70 – 90Combined sources21

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3G27X-ray2.10A1-96[»]
ProteinModelPortaliP68661
SMRiP68661
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP68661

Family & Domainsi

Sequence similaritiesi

Belongs to the YbcO family.Curated

Phylogenomic databases

eggNOGiENOG4105RWQ Bacteria
ENOG4111WGW LUCA
HOGENOMiHOG000122769
OMAiFRSRAWR

Family and domain databases

InterProiView protein in InterPro
IPR010774 DUF1364
PfamiView protein in Pfam
PF07102 DUF1364, 1 hit

Sequencei

Sequence statusi: Complete.

P68661-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLRKAARG RECQVRIPGV CNGNPETSVL AHIRLTGLCG TGTKPPDLIA
60 70 80 90
TIACSACHDE IDRRTHFVDA GYAKECALEG MARTQVIWLK EGVIKA
Length:96
Mass (Da):10,348
Last modified:December 7, 2004 - v1
Checksum:iAB066A8AE7B273C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92587 Genomic DNA Translation: CAA63320.1
U82598 Genomic DNA Translation: AAB40745.1
U00096 Genomic DNA Translation: AAC73650.1
AP009048 Genomic DNA Translation: BAE76324.1
PIRiC64787
RefSeqiNP_415081.1, NC_000913.3
WP_000774486.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73650; AAC73650; b0549
BAE76324; BAE76324; BAE76324
GeneIDi945147
KEGGiecj:JW0537
eco:b0549
PATRICifig|511145.12.peg.570

Similar proteinsi

Entry informationi

Entry nameiYBCO_ECOLI
AccessioniPrimary (citable) accession number: P68661
Secondary accession number(s): Q2MBN2, Q37872, Q47271
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: December 7, 2004
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health