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Protein

Protein FixC

Gene

fixC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could be part of an electron transfer system required for anaerobic carnitine reduction.

Cofactori

FADCurated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 28FAD or NAD or NADPSequence analysisAdd BLAST17

GO - Molecular functioni

GO - Biological processi

  • carnitine metabolic process Source: EcoliWiki

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Transport
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciEcoCyc:EG11564-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FixC
Gene namesi
Name:fixC
Synonyms:yaaS
Ordered Locus Names:b0043, JW0042
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11564 fixC

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002006901 – 428Protein FixCAdd BLAST428

Proteomic databases

PaxDbiP68644
PRIDEiP68644

Interactioni

Protein-protein interaction databases

BioGridi4262204, 7 interactors
IntActiP68644, 8 interactors
STRINGi316385.ECDH10B_0044

Structurei

3D structure databases

ProteinModelPortaliP68644
SMRiP68644
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ETF-QO/FixC family.Curated

Phylogenomic databases

eggNOGiENOG4105DWH Bacteria
COG0644 LUCA
HOGENOMiHOG000018936
InParanoidiP68644
KOiK00313
OMAiKPNRYTI
PhylomeDBiP68644

Family and domain databases

Gene3Di3.50.50.60, 1 hit
InterProiView protein in InterPro
IPR002938 FAD-bd
IPR036188 FAD/NAD-bd_sf
PfamiView protein in Pfam
PF01494 FAD_binding_3, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits

Sequencei

Sequence statusi: Complete.

P68644-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEDIFDAII VGAGLAGSVA ALVLAREGAQ VLVIERGNSA GAKNVTGGRL
60 70 80 90 100
YAHSLEHIIP GFADSAPVER LITHEKLAFM TEKSAMTMDY CNGDETSPSQ
110 120 130 140 150
RSYSVLRSKF DAWLMEQAEE AGAQLITGIR VDNLVQRDGK VVGVEADGDV
160 170 180 190 200
IEAKTVILAD GVNSILAEKL GMAKRVKPTD VAVGVKELIE LPKSVIEDRF
210 220 230 240 250
QLQGNQGAAC LFAGSPTDGL MGGGFLYTNE NTLSLGLVCG LHHLHDAKKS
260 270 280 290 300
VPQMLEDFKQ HPAVAPLIAG GKLVEYSAHV VPEAGINMLP ELVGDGVLIA
310 320 330 340 350
GDAAGMCMNL GFTIRGMDLA IAAGEAAAKT VLSAMKSDDF SKQKLAEYRQ
360 370 380 390 400
HLESGPLRDM RMYQKLPAFL DNPRMFSGYP ELAVGVARDL FTIDGSAPEL
410 420
MRKKILRHGK KVGFINLIKD GMKGVTVL
Length:428
Mass (Da):45,703
Last modified:December 7, 2004 - v1
Checksum:i4D089EE9A30C7FBC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti1 – 3MSE → MT (PubMed:7473063).Curated3
Sequence conflicti64D → E in CAA50799 (PubMed:1630901).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73154.1
AP009048 Genomic DNA Translation: BAB96611.2
X71977 Genomic DNA Translation: CAA50799.1
PIRiC64725
RefSeqiNP_414585.1, NC_000913.3
WP_001287715.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73154; AAC73154; b0043
BAB96611; BAB96611; BAB96611
GeneIDi948958
KEGGiecj:JW0042
eco:b0043
PATRICifig|1411691.4.peg.2240

Similar proteinsi

Entry informationi

Entry nameiFIXC_ECOLI
AccessioniPrimary (citable) accession number: P68644
Secondary accession number(s): P31575, P75626
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: December 7, 2004
Last modified: March 28, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
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