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Protein

Telomere-binding protein I6

Gene

I6L

Organism
Vaccinia virus (strain Copenhagen) (VACV)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Binds to the hairpin form of the viral telomeric sequence. Might direct genome encapsidation into the virus particle (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Telomere-binding protein I6
Gene namesi
ORF Names:I6L
OrganismiVaccinia virus (strain Copenhagen) (VACV)
Taxonomic identifieri10249 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000008269 Componenti: Genome

Subcellular locationi

  • Virion By similarity

  • Note: Present in the virus core.By similarity

GO - Cellular componenti

  • virion Source: UniProtKB-SubCell

Keywords - Cellular componenti

Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000995781 – 382Telomere-binding protein I6Add BLAST382

Structurei

3D structure databases

SMRiP68463.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chordopoxvirinae I6 family.Curated

Phylogenomic databases

OrthoDBiVOG090000CG.

Family and domain databases

InterProiView protein in InterPro
IPR007674. Poxvirus_36kDa_major_membrane.
IPR022219. Poxvirus_I6_C.
PfamiView protein in Pfam
PF12562. DUF3746. 1 hit.
PF04595. Pox_I6. 1 hit.

Sequencei

Sequence statusi: Complete.

P68463-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNFVKQVAS KSLKPTKKLS PSDEVISLNE CIISFNLDNF YYCNDGLFTK
60 70 80 90 100
PINTPEDVLK SLLIMESFAY EKMIIKGLIK ILISRAYIND IYFTPFGWLT
110 120 130 140 150
GVDDDPETHV VIKIIFNSSL ISIKSQVIEY LKPYNVNNLS VLTTEKELSI
160 170 180 190 200
NTFNVPDSIP MSIISFFPFD TDFILVILFF GVYNDSYCGI SYISPKERLP
210 220 230 240 250
YIIEILKPLV SEINMLSDEI GRTSSIRIFN STSVKKFPTN TLTSICEIVY
260 270 280 290 300
SFDESSFPTP KTFTPLNASP YIPKKIVSLL DLPSNVEIKA ISRGGVDFIT
310 320 330 340 350
HINNKRLNTI LVIAKDNFLK NSTFSGTFIK ENIIWKGIYT YRIIKSSFPV
360 370 380
PTIKSVTNKK KICKKHCFVN SQYTTRTLSH IL
Length:382
Mass (Da):43,454
Last modified:November 23, 2004 - v1
Checksum:i4D0F72666DEE1307
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35027 Genomic DNA. Translation: AAA48062.1.
PIRiF29889. WZVZI6.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiI6_VACCC
AccessioniPrimary (citable) accession number: P68463
Secondary accession number(s): P12925
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: November 23, 2004
Last modified: March 15, 2017
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families