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Protein

Late transcription elongation factor G2

Gene

VACWR080

Organism
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in postreplicative transcription elongation on intermediate and late genes.1 Publication

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Late transcription elongation factor G2
Alternative name(s):
Protein G2
Gene namesi
Ordered Locus Names:VACWR080
ORF Names:G2R
OrganismiVaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Taxonomic identifieri10254 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiBos taurus (Bovine) [TaxID: 9913]
Proteomesi
  • UP000000344 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000995251 – 220Late transcription elongation factor G2Add BLAST220

Expressioni

Keywords - Developmental stagei

Early protein

Interactioni

Subunit structurei

Interacts with H5 and A18. Might be part of a transcription complex composed at least of G2, A18, and H5.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
VACWR103P072424EBI-7273347,EBI-7272435

Protein-protein interaction databases

IntActiP68456. 2 interactors.
MINTiMINT-130661.

Family & Domainsi

Sequence similaritiesi

Belongs to the chordopoxvirinae G2 family.Curated

Phylogenomic databases

OrthoDBiVOG090000NJ.

Family and domain databases

InterProiView protein in InterPro
IPR008446. Chordopox_G2.
PfamiView protein in Pfam
PF05796. Chordopox_G2. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD023269. Chordopox_G2. 1 hit.

Sequencei

Sequence statusi: Complete.

P68456-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFRDLILFN LSKFLLTEDE ESLEIVSSLC RGFEISYDDL ITYFPDRKYH
60 70 80 90 100
KYISKVFEHV DLSEELSMEF HDTTLRDLVY LRLYKYSKCI RPCYKLGDNL
110 120 130 140 150
KGIVVIKDRN IYIREANDDL IEYLLKEYTP QIYTYSNERV PITGSKLILC
160 170 180 190 200
GFSQVTFMAY TTSHITTNKK VDVLVSKKCI DELVDPINYQ ILQNLFDKGS
210 220
GTINKILRKI FYSVTGGQTP
Length:220
Mass (Da):25,744
Last modified:November 23, 2004 - v1
Checksum:iFA97B1E8F419D1A2
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti151G → R in strain: Temperature-sensitive mutant. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03399 Genomic DNA. Translation: AAB59813.1.
AY243312 Genomic DNA. Translation: AAO89359.1.
PIRiA39986. QQVZW1.
RefSeqiYP_232962.1. NC_006998.1.

Genome annotation databases

GeneIDi3707536.
KEGGivg:3707536.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03399 Genomic DNA. Translation: AAB59813.1.
AY243312 Genomic DNA. Translation: AAO89359.1.
PIRiA39986. QQVZW1.
RefSeqiYP_232962.1. NC_006998.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP68456. 2 interactors.
MINTiMINT-130661.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3707536.
KEGGivg:3707536.

Phylogenomic databases

OrthoDBiVOG090000NJ.

Family and domain databases

InterProiView protein in InterPro
IPR008446. Chordopox_G2.
PfamiView protein in Pfam
PF05796. Chordopox_G2. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD023269. Chordopox_G2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiG2_VACCW
AccessioniPrimary (citable) accession number: P68456
Secondary accession number(s): P21023, Q76ZU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: November 23, 2004
Last modified: February 15, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.