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Protein

Protein E7

Gene

E7R

Organism
Vaccinia virus (strain Copenhagen) (VACV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein E7
Gene namesi
ORF Names:E7R
OrganismiVaccinia virus (strain Copenhagen) (VACV)
Taxonomic identifieri10249 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000008269 Componenti: Genome

Subcellular locationi

  • Host cytoplasm 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi2G → A: Complete loss of myristoylation. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved; by host
ChainiPRO_00000994582 – 166Protein E7Add BLAST165

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycine; by host1 Publication1

Post-translational modificationi

Myristoylated.1 Publication

Keywords - PTMi

Lipoprotein, Myristate

Structurei

3D structure databases

SMRiP68447.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chordopoxvirinae E7 family.Curated

Phylogenomic databases

OrthoDBiVOG090000XK.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P68447-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTAATIQTP TKLMNKENAE MILEKIVDHI VMYISDESSD SENNPEYIDF
60 70 80 90 100
RNRYEDYRSL IIKSDHEFVK LCKNHAEKSS PETQQMIIKH IYEQYLIPVS
110 120 130 140 150
EVLLKPIMSM GDIITYNGCK DNEWMLEQLS TLNFNNLRTW NSCSIGNVTR
160
LFYTFFSYLM KDKLNI
Length:166
Mass (Da):19,512
Last modified:January 23, 2007 - v3
Checksum:i0E527693710FD087
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35027 Genomic DNA. Translation: AAA48045.1.
PIRiB42509.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35027 Genomic DNA. Translation: AAA48045.1.
PIRiB42509.

3D structure databases

SMRiP68447.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiVOG090000XK.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiE7_VACCC
AccessioniPrimary (citable) accession number: P68447
Secondary accession number(s): P21048
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: January 23, 2007
Last modified: April 12, 2017
This is version 34 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.