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Protein

Protein E7

Gene

VACWR063

Organism
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein E7
Gene namesi
Ordered Locus Names:VACWR063
ORF Names:E7R
OrganismiVaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Taxonomic identifieri10254 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiBos taurus (Bovine) [TaxID: 9913]
Proteomesi
  • UP000000344 Componenti: Genome

Subcellular locationi

  • Host cytoplasm 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi2G → A: Complete loss of myristoylation. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved; by host
ChainiPRO_00000994592 – 166Protein E7Add BLAST165

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycine; by host1 Publication1

Post-translational modificationi

Myristoylated.1 Publication

Keywords - PTMi

Lipoprotein, Myristate

Interactioni

Protein-protein interaction databases

ELMiP68446.
IntActiP68446. 1 interactor.
MINTiMINT-130795.

Structurei

3D structure databases

SMRiP68446.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chordopoxvirinae E7 family.Curated

Phylogenomic databases

OrthoDBiVOG090000XK.

Family and domain databases

InterProiView protein in InterPro
IPR035345. E7R.
PfamiView protein in Pfam
PF17467. E7R. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD027155. PD027155. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P68446-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTAATIQTP TKLMNKENAE MILEKIVDHI VMYISDESSD SENNPEYIDF
60 70 80 90 100
RNRYEDYRSL IIKSDHEFVK LCKNHAEKSS PETQQMIIKH IYEQYLIPVS
110 120 130 140 150
EVLLKPIMSM GDIITYNGCK DNEWMLEQLS TLNFNNLRTW NSCSIGNVTR
160
LFYTFFSYLM KDKLNI
Length:166
Mass (Da):19,512
Last modified:January 23, 2007 - v3
Checksum:i0E527693710FD087
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36339 Genomic DNA. Translation: AAB59827.1.
M13213 Genomic DNA. Translation: AAA98421.1.
AY243312 Genomic DNA. Translation: AAO89342.1.
RefSeqiYP_232945.1. NC_006998.1.

Genome annotation databases

GeneIDi3707596.
KEGGivg:3707596.

Similar proteinsi

Entry informationi

Entry nameiE7_VACCW
AccessioniPrimary (citable) accession number: P68446
Secondary accession number(s): P21048, Q76ZV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 44 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families