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Protein

Myoglobin

Gene

MB

Organism
Delphinus delphis (Short-beaked common dolphin)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi65 – 651Iron (heme distal ligand)
Metal bindingi94 – 941Iron (heme proximal ligand)

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiDelphinus delphis (Short-beaked common dolphin)
Taxonomic identifieri9728 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaCetaceaOdontocetiDelphinidaeDelphinus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved2 Publications
Chaini2 – 154153MyoglobinPRO_0000053287Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei4 – 41PhosphoserineBy similarity
Modified residuei68 – 681PhosphothreonineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP68276.

Structurei

3D structure databases

ProteinModelPortaliP68276.
SMRiP68276. Positions 1-154.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG107340.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P68276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWQL VLNVWGKVEA DLAGHGQDVL IRLFKGHPET LEKFDKFKHL
60 70 80 90 100
KTEADMKASE DLKKHGNTVL TALGAILKKK GHHDAELKPL AQSHATKHKI
110 120 130 140 150
PIKYLEFISE AIIHVLHSRH PAEFGADAQG AMNKALELFR KDIAAKYKEL

GFHG
Length:154
Mass (Da):17,188
Last modified:January 23, 2007 - v2
Checksum:i0D2879547F28AC1A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti22 – 221L → V AA sequence (PubMed:11945989).Curated
Sequence conflicti29 – 291V → I AA sequence (PubMed:11945989).Curated
Sequence conflicti67 – 671N → D AA sequence (PubMed:5473803).Curated
Sequence conflicti123 – 1231E → Q AA sequence (PubMed:5473803).Curated

Sequence databases

PIRiA26230. MYDDBS.

Cross-referencesi

Sequence databases

PIRiA26230. MYDDBS.

3D structure databases

ProteinModelPortaliP68276.
SMRiP68276. Positions 1-154.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP68276.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG107340.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMYG_DELDE
AccessioniPrimary (citable) accession number: P68276
Secondary accession number(s): P02172, P02175
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: December 9, 2015
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.