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Protein

Stationary-phase-induced ribosome-associated protein

Gene

sra

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.2 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11508-MONOMER.
ECOL316407:JW5962-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Stationary-phase-induced ribosome-associated protein
Short name:
Protein D
Short name:
SRA
Alternative name(s):
30S ribosomal protein S22
Gene namesi
Name:sra
Synonyms:rpsV
Ordered Locus Names:b1480, JW5962
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11508. sra.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
  • cytosolic small ribosomal subunit Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Disruption phenotypei

Not essential, a quadruple raiA-hpf-rmf-sra knockout strain is significantly outcompeted by wild-type after 4 days growth (PubMed:17277072).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4545Stationary-phase-induced ribosome-associated proteinPRO_0000208690Add
BLAST

Proteomic databases

EPDiP68191.
PaxDbiP68191.
PRIDEiP68191.

Expressioni

Inductioni

Induced upon entry into stationary phase, this is controlled at least in part by the RpoS sigma factor.

Interactioni

Subunit structurei

Associates exclusively with the 30S subunit; there is 0.1 copy per ribosome in the exponential phase and 0.4 copies per ribosome in the stationary phase. This is also true for several other K12 derivatives and strain B/R.1 Publication

Protein-protein interaction databases

BioGridi4260209. 7 interactions.
DIPiDIP-48175N.
IntActiP68191. 1 interaction.
MINTiMINT-1322613.
STRINGi511145.b1480.

Structurei

3D structure databases

ProteinModelPortaliP68191.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SRA family.Curated

Phylogenomic databases

eggNOGiENOG4107AV5. Bacteria.
ENOG410XU1Y. LUCA.
HOGENOMiHOG000267917.
KOiK02972.

Family and domain databases

InterProiIPR012607. Ribosomal_S22.
[Graphical view]
PfamiPF08136. Ribosomal_S22. 1 hit.
[Graphical view]
ProDomiPD049510. Ribosomal_S22. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P68191-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MKSNRQARHI LGLDHKISNQ RKIVTEGDKS SVVNNPTGRK RPAEK
Length:45
Mass (Da):5,096
Last modified:October 25, 2004 - v1
Checksum:i81DB6E2D2E222C2F
GO

Mass spectrometryi

Molecular mass is 5095.9 Da from positions 1 - 45. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13179 Genomic DNA. Translation: BAA02474.1.
X55956 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74553.1.
AP009048 Genomic DNA. Translation: BAE76452.1.
PIRiC64901.
RefSeqiNP_415997.1. NC_000913.3.
WP_000841554.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74553; AAC74553; b1480.
BAE76452; BAE76452; BAE76452.
GeneIDi946030.
KEGGiecj:JW5962.
eco:b1480.
PATRICi32118254. VBIEscCol129921_1547.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13179 Genomic DNA. Translation: BAA02474.1.
X55956 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74553.1.
AP009048 Genomic DNA. Translation: BAE76452.1.
PIRiC64901.
RefSeqiNP_415997.1. NC_000913.3.
WP_000841554.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP68191.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260209. 7 interactions.
DIPiDIP-48175N.
IntActiP68191. 1 interaction.
MINTiMINT-1322613.
STRINGi511145.b1480.

Proteomic databases

EPDiP68191.
PaxDbiP68191.
PRIDEiP68191.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74553; AAC74553; b1480.
BAE76452; BAE76452; BAE76452.
GeneIDi946030.
KEGGiecj:JW5962.
eco:b1480.
PATRICi32118254. VBIEscCol129921_1547.

Organism-specific databases

EchoBASEiEB1471.
EcoGeneiEG11508. sra.

Phylogenomic databases

eggNOGiENOG4107AV5. Bacteria.
ENOG410XU1Y. LUCA.
HOGENOMiHOG000267917.
KOiK02972.

Enzyme and pathway databases

BioCyciEcoCyc:EG11508-MONOMER.
ECOL316407:JW5962-MONOMER.

Miscellaneous databases

PROiP68191.

Family and domain databases

InterProiIPR012607. Ribosomal_S22.
[Graphical view]
PfamiPF08136. Ribosomal_S22. 1 hit.
[Graphical view]
ProDomiPD049510. Ribosomal_S22. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiSRA_ECOLI
AccessioniPrimary (citable) accession number: P68191
Secondary accession number(s): P28690, Q2MBA4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: October 25, 2004
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Was originally thought to be a ribosomal protein.1 Publication

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.