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Protein

Myoglobin

Gene

MB

Organism
Equus caballus (Horse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Iron (heme distal ligand)1 Publication1
Metal bindingi94Iron (heme proximal ligand)Combined sources3 Publications1

GO - Molecular functioni

Keywordsi

Molecular functionMuscle protein
Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

SABIO-RKiP68082

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiEquus caballus (Horse)
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 28

Organism-specific databases

VGNCiVGNC:20004 MB

Pathology & Biotechi

Protein family/group databases

Allergomei10877 Equ c Myoglobin

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved3 Publications
ChainiPRO_00000533022 – 154MyoglobinAdd BLAST153

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP68082
PRIDEiP68082

PTM databases

CarbonylDBiP68082

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000015509

Structurei

Secondary structure

1154
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 19Combined sources15
Helixi22 – 36Combined sources15
Helixi38 – 41Combined sources4
Helixi45 – 47Combined sources3
Helixi53 – 58Combined sources6
Helixi60 – 96Combined sources37
Helixi102 – 119Combined sources18
Turni121 – 123Combined sources3
Helixi126 – 149Combined sources24
Turni150 – 153Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AZIX-ray2.00A2-154[»]
1BJEX-ray1.80A2-154[»]
1DWRX-ray1.45A2-154[»]
1DWSX-ray1.45A2-154[»]
1DWTX-ray1.40A2-154[»]
1GJNX-ray1.35A2-154[»]
1HRMX-ray1.70A2-154[»]
1HSYX-ray1.90A2-154[»]
1NPFX-ray1.90A2-154[»]
1NPGX-ray1.70A2-154[»]
1NZ2X-ray1.90A2-154[»]
1NZ3X-ray1.60A2-154[»]
1NZ4X-ray1.80A2-154[»]
1NZ5X-ray1.70A2-154[»]
1RSEX-ray1.70A2-154[»]
1WLAX-ray1.70A2-154[»]
1XCHX-ray1.70A2-154[»]
1YMAX-ray2.00A2-154[»]
1YMBX-ray1.90A2-154[»]
1YMCX-ray2.00A2-154[»]
2FRFX-ray1.20A2-154[»]
2FRIX-ray1.60X2-154[»]
2FRJX-ray1.30X2-154[»]
2FRKX-ray1.30X2-154[»]
2IN4X-ray2.15A2-154[»]
2NSRX-ray1.90A2-154[»]
2NSSX-ray2.00A2-154[»]
2O58X-ray1.65X2-154[»]
2O5BX-ray2.00X2-154[»]
2O5LX-ray1.70X2-154[»]
2O5MX-ray1.65X2-154[»]
2O5OX-ray1.60X2-154[»]
2O5QX-ray1.90X2-154[»]
2O5SX-ray1.60X2-154[»]
2O5TX-ray1.60X2-154[»]
2V1EX-ray1.30A2-154[»]
2V1FX-ray1.20A2-154[»]
2V1GX-ray1.35A2-154[»]
2V1HX-ray1.30A2-154[»]
2V1IX-ray1.20A2-154[»]
2V1JX-ray1.40A2-154[»]
2V1KX-ray1.25A2-154[»]
2VLXX-ray1.30A2-154[»]
2VLYX-ray1.60A2-154[»]
2VLZX-ray1.50A2-154[»]
2VM0X-ray1.60A2-154[»]
3BA2X-ray1.80A2-154[»]
3HC9X-ray2.00A2-154[»]
3HENX-ray1.90A2-154[»]
3HEOX-ray2.00A2-154[»]
3HEPX-ray1.95A2-154[»]
3LR7X-ray1.60A2-154[»]
3LR9X-ray1.55A2-154[»]
3RJ6X-ray1.23A/B2-154[»]
3RJNX-ray1.90B2-154[»]
3V2VX-ray1.65A2-154[»]
3V2ZX-ray1.65A2-154[»]
3VAUX-ray1.70A2-154[»]
3VM9X-ray1.05A/B2-154[»]
3WFTX-ray1.30A2-154[»]
3WFUX-ray1.35A2-154[»]
3WI8X-ray2.20A2-154[»]
3WYOX-ray2.00A/B/C/D2-154[»]
4DC7X-ray1.50A2-153[»]
4DC8X-ray1.50A2-153[»]
4NS2X-ray1.18A1-154[»]
4TWUX-ray1.08A1-154[»]
4TWVX-ray1.06A1-154[»]
5AZQX-ray1.40A2-154[»]
5AZRX-ray1.20A2-154[»]
5CMVX-ray1.80A2-153[»]
5CN4X-ray1.80A2-153[»]
5CN5X-ray1.80A2-153[»]
5CN6X-ray1.80A2-153[»]
5CN7X-ray1.80A2-153[»]
5CN8X-ray1.80A2-153[»]
5CN9X-ray1.80A2-153[»]
5CNBX-ray1.80A2-153[»]
5CNCX-ray1.80A2-153[»]
5CNDX-ray1.80A2-153[»]
5CNEX-ray1.80A2-153[»]
5CNFX-ray1.80A2-153[»]
5CNGX-ray1.80A2-153[»]
5D5RX-ray1.60A2-153[»]
5YL3X-ray1.50A1-154[»]
ProteinModelPortaliP68082
SMRiP68082
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP68082

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
GeneTreeiENSGT00730000110844
HOGENOMiHOG000070111
HOVERGENiHBG107340
InParanoidiP68082
KOiK21892
OMAiLFRNDIA
OrthoDBiEOG091G0OAO
TreeFamiTF332967

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002335 Myoglobin
PANTHERiPTHR11442:SF5 PTHR11442:SF5, 1 hit
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00613 MYOGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P68082-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWQQ VLNVWGKVEA DIAGHGQEVL IRLFTGHPET LEKFDKFKHL
60 70 80 90 100
KTEAEMKASE DLKKHGTVVL TALGGILKKK GHHEAELKPL AQSHATKHKI
110 120 130 140 150
PIKYLEFISD AIIHVLHSKH PGDFGADAQG AMTKALELFR NDIAAKYKEL

GFQG
Length:154
Mass (Da):17,083
Last modified:January 23, 2007 - v2
Checksum:i20EABC4A66ACE975
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123D → N AA sequence (PubMed:4902609).Curated1

Sequence databases

PIRiA91098 MYHO
RefSeqiNP_001157488.1, NM_001164016.1
UniGeneiEca.16922

Genome annotation databases

EnsembliENSECAT00000018976; ENSECAP00000015509; ENSECAG00000017982
GeneIDi100054434
KEGGiecb:100054434

Similar proteinsi

Entry informationi

Entry nameiMYG_HORSE
AccessioniPrimary (citable) accession number: P68082
Secondary accession number(s): P02188
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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