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Protein

Substance P

Gene

TAC1

Organism
Equus caballus (Horse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

GO - Biological processi

Keywordsi

Molecular functionNeuropeptide, Neurotransmitter

Names & Taxonomyi

Protein namesi
Recommended name:
Substance P
Gene namesi
Name:TAC1
Synonyms:NKA, NKNA, TAC2
OrganismiEquus caballus (Horse)
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000444201 – 11Substance PAdd BLAST11

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei11Methionine amide1 Publication1

Keywords - PTMi

Amidation

Family & Domainsi

Sequence similaritiesi

Belongs to the tachykinin family.Curated

Phylogenomic databases

HOVERGENiHBG079260.

Family and domain databases

InterProiView protein in InterPro
IPR013055. Tachy_Neuro_lke_CS.
IPR008215. Tachykinin_dom.
PfamiView protein in Pfam
PF02202. Tachykinin. 1 hit.
PROSITEiView protein in PROSITE
PS00267. TACHYKININ. 1 hit.

Sequencei

Sequence statusi: Complete.

Length:11
Mass (Da):1,349
Last modified:July 21, 1986 - v1
Checksum:i3E757FE3C9D6C6C7
GO

Sequence databases

PIRiA01558. SPHO.

Similar proteinsi

Entry informationi

Entry nameiTKNA_HORSE
AccessioniPrimary (citable) accession number: P67933
Secondary accession number(s): P01290
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 12, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families