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Protein

Copper homeostasis protein CutC

Gene

cutC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in copper homeostasis.

GO - Molecular functioni

GO - Biological processi

  • cellular copper ion homeostasis Source: EcoliWiki
  • copper ion homeostasis Source: EcoliWiki
  • response to copper ion Source: EcoliWiki
Complete GO annotation...

Keywords - Ligandi

Copper

Enzyme and pathway databases

BioCyciEcoCyc:G7024-MONOMER.
ECOL316407:JW1863-MONOMER.

Protein family/group databases

TCDBi9.B.158.1.2. the cut copper homeostasis (cut) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Copper homeostasis protein CutC
Gene namesi
Name:cutC
Synonyms:cutCM
Ordered Locus Names:b1874, JW1863
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12956. cutC.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002150641 – 248Copper homeostasis protein CutCAdd BLAST248

Proteomic databases

PaxDbiP67826.
PRIDEiP67826.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

BioGridi4262958. 15 interactors.
IntActiP67826. 6 interactors.
STRINGi511145.b1874.

Structurei

3D structure databases

ProteinModelPortaliP67826.
SMRiP67826.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CutC family.Curated

Phylogenomic databases

eggNOGiENOG4106N3A. Bacteria.
COG3142. LUCA.
HOGENOMiHOG000100908.
InParanoidiP67826.
KOiK06201.
OMAiRIELCAG.
PhylomeDBiP67826.

Family and domain databases

Gene3Di3.20.20.380. 1 hit.
HAMAPiMF_00795. CutC. 1 hit.
InterProiIPR005627. Cu_homeostasis_CutC.
IPR023648. Cu_homeostasis_CutC_dom.
[Graphical view]
PANTHERiPTHR12598. PTHR12598. 1 hit.
PfamiPF03932. CutC. 1 hit.
[Graphical view]
SUPFAMiSSF110395. SSF110395. 1 hit.

Sequencei

Sequence statusi: Complete.

P67826-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLEICCYS MECALTAQQN GADRVELCAA PKEGGLTPSL GVLKSVRQRV
60 70 80 90 100
TIPVHPIIRP RGGDFCYSDG EFAAILEDVR TVRELGFPGL VTGVLDVDGN
110 120 130 140 150
VDMPRMEKIM AAAGPLAVTF HRAFDMCANP LYTLNNLAEL GIARVLTSGQ
160 170 180 190 200
KSDALQGLSK IMELIAHRDA PIIMAGAGVR AENLHHFLDA GVLEVHSSAG
210 220 230 240
AWQASPMRYR NQGLSMSSDE HADEYSRYIV DGAAVAEMKG IIERHQAK
Length:248
Mass (Da):26,762
Last modified:October 11, 2004 - v1
Checksum:i998A55A417A010B2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti18Q → H in AAA89202 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L38618 Genomic DNA. Translation: AAA89202.1.
U00096 Genomic DNA. Translation: AAC74944.2.
AP009048 Genomic DNA. Translation: BAA15684.1.
PIRiB64950.
RefSeqiWP_001185741.1. NZ_LN832404.1.
YP_025309.2. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC74944; AAC74944; b1874.
BAA15684; BAA15684; BAA15684.
GeneIDi2847756.
KEGGiecj:JW1863.
eco:b1874.
PATRICi32119073. VBIEscCol129921_1954.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L38618 Genomic DNA. Translation: AAA89202.1.
U00096 Genomic DNA. Translation: AAC74944.2.
AP009048 Genomic DNA. Translation: BAA15684.1.
PIRiB64950.
RefSeqiWP_001185741.1. NZ_LN832404.1.
YP_025309.2. NC_000913.3.

3D structure databases

ProteinModelPortaliP67826.
SMRiP67826.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262958. 15 interactors.
IntActiP67826. 6 interactors.
STRINGi511145.b1874.

Protein family/group databases

TCDBi9.B.158.1.2. the cut copper homeostasis (cut) family.

Proteomic databases

PaxDbiP67826.
PRIDEiP67826.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74944; AAC74944; b1874.
BAA15684; BAA15684; BAA15684.
GeneIDi2847756.
KEGGiecj:JW1863.
eco:b1874.
PATRICi32119073. VBIEscCol129921_1954.

Organism-specific databases

EchoBASEiEB2790.
EcoGeneiEG12956. cutC.

Phylogenomic databases

eggNOGiENOG4106N3A. Bacteria.
COG3142. LUCA.
HOGENOMiHOG000100908.
InParanoidiP67826.
KOiK06201.
OMAiRIELCAG.
PhylomeDBiP67826.

Enzyme and pathway databases

BioCyciEcoCyc:G7024-MONOMER.
ECOL316407:JW1863-MONOMER.

Miscellaneous databases

PROiP67826.

Family and domain databases

Gene3Di3.20.20.380. 1 hit.
HAMAPiMF_00795. CutC. 1 hit.
InterProiIPR005627. Cu_homeostasis_CutC.
IPR023648. Cu_homeostasis_CutC_dom.
[Graphical view]
PANTHERiPTHR12598. PTHR12598. 1 hit.
PfamiPF03932. CutC. 1 hit.
[Graphical view]
SUPFAMiSSF110395. SSF110395. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCUTC_ECOLI
AccessioniPrimary (citable) accession number: P67826
Secondary accession number(s): P46719, P76294
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.