P67553 (YNFC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0257 lipoprotein YnfC

Gene names

Name:	ynfC
Ordered Locus Names:	b1585, JW5258

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Lipid-anchor Potential HAMAP-Rule MF_01065.
Sequence similarities	Belongs to the UPF0257 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 16	16	Potential
	Chain	17 – 236	220	UPF0257 lipoprotein YnfC HAMAP-Rule MF_01065		PRO_0000036261
Amino acid modifications
	Lipidation	17	1	N-palmitoyl cysteine Potential
	Lipidation	17	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	P67553 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: DC2A48777061BD21	FASTA	236	26,507
	10 20 30 40 50 60 MKYKLLPCLL AIFLTGCDRT EVTLSFTPEM ASFSNEFDFD PLRGPVKDFT QTLMDEQGEV 70 80 90 100 110 120 TKRVSGTLSE EGCFDSLELL DLENNTVVAL VLDANYYRDA ETLEKRVRLQ GKCQLAELPS 130 140 150 160 170 180 AGVSWETDDN GFVIKASSKQ MQMEYRYDDQ GYPLGKTTKS NDKTLSVSAT PSTDPIKKLD 190 200 210 220 230 YTAVTLLNNQ RVGNVKQSCE YDSHANPVDC QLIIVDEGVK PAVERVYTIK NTIDYY

References

[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74657.2. AP009048 Genomic DNA. Translation: BAE76478.1.
PIR	C64914.
RefSeq	NP_416102.2. NC_000913.2. YP_489848.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P67553.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b1585.
Proteomic databases
PRIDE	P67553.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC74657; AAC74657; b1585. BAE76478; BAE76478; BAE76478.
GeneID	12931241. 946131.
KEGG	ecj:Y75_p1561. eco:b1585.
PATRIC	32118472. VBIEscCol129921_1656.
Organism-specific databases
EchoBASE	EB3602.
EcoGene	EG13841. ynfC.
Phylogenomic databases
eggNOG	NOG10209.
HOGENOM	HOG000120796.
OMA	RYDAEGY.
ProtClustDB	PRK02939.
Enzyme and pathway databases
BioCyc	EcoCyc:G6843-MONOMER. ECOL316407:JW5258-MONOMER.
Gene expression databases
Genevestigator	P67553.
Family and domain databases
HAMAP	MF_01065. UPF0257.
InterPro	IPR010646. UPF0257. [Graphical view]
Pfam	PF06788. UPF0257. 1 hit. [Graphical view]
ProDom	PD120112. UPF0257. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YNFC_ECOLI

Accession

Primary (citable) accession number: P67553
Secondary accession number(s): P76171, Q2MB78

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program