Reviewed,
UniProtKB/Swiss-Prot P67472 (ALF1_STAAM)
Last modified
January 19, 2010.
Version 31.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Fructose-bisphosphate aldolase class 1 EC=4.1.2.13 Alternative name(s): Fructose-biphosphate aldolase class I Short name=FBP aldolase | ||||
| Gene names |
| ||||
| Organism | Staphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 158878 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 296 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP MF_00729 |
| Pathway | Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP MF_00729 |
| Sequence similarities | Belongs to the class I fructose-bisphosphate aldolase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Glycolysis |
| Ligand | Schiff base |
| Molecular function | Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycolysis Inferred from electronic annotation. Source: HAMAP |
| Molecular function | fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed By similarity | ||||||
| Chain | 2 – 296 | 295 | Fructose-bisphosphate aldolase class 1 HAMAP MF_00729 | PRO_0000216904 | |||||
Sites | |||||||||
| Active site | 175 | 1 | Proton acceptor By similarity | ||||||
| Active site | 212 | 1 | Schiff-base intermediate with dihydroxyacetone-P By similarity | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "Whole genome sequencing of meticillin-resistant Staphylococcus aureus." Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y. Hiramatsu K.Lancet 357:1225-1240(2001) [PubMed: 11418146] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000017 Genomic DNA. Translation: BAB58768.1. |
| RefSeq | NP_373130.1. |
3D structure databases | |
| SMR | P67472. Positions 1-294. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P67472. |
2-D gel databases | |
| World-2DPAGE | 0002:P67472. |
Genome annotation databases | |
| GeneID | 1122631. |
| GenomeReviews | Gene locus SAV2606 in contig BA000017_GR. |
| KEGG | sav:SAV2606. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG3588. |
| HOGENOM | HBG307137. |
| OMA | GTKMRSV. |
Enzyme and pathway databases | |
| BioCyc | SAUR158878:SAV2606-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00729. FBP_aldolase_1. [Tree] |
| InterPro | IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| PANTHER | PTHR11627. Aldolase_I. 1 hit. |
| Pfam | PF00274. Glycolytic. 1 hit. [Graphical view] |
| PROSITE | PS00158. ALDOLASE_CLASS_I. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ALF1_STAAM | ||||||||
| Accession | Primary (citable) accession number: P67472 Secondary accession number(s): Q99R31 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


