Reviewed, UniProtKB/Swiss-Prot P67455 (EX7S_BRUSU)

Names and origin

Protein names

Recommended name:
    Exodeoxyribonuclease 7 small subunit
    EC=3.1.11.6
Alternative name(s):
    Exodeoxyribonuclease VII small subunit
      Short name=Exonuclease VII small subunit

Gene names

Name:	xseB
Ordered Locus Names:	BR0431

Organism

Brucella suis [Complete proteome] [HAMAP]

Taxonomic identifier

29461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	83 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity.
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP MF_00337
Subunit structure	Heterooligomer composed of large and small subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the xseB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Exonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 83	83	Exodeoxyribonuclease 7 small subunit HAMAP MF_00337		PRO_0000206930

Sequences

	Sequence		Length	Mass (Da)
	P67455-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 8B51C2BA8FE9FF1E	FASTA	83	9,322
	10 20 30 40 50 60 MTEPSNADIA VMSFEDALKQ LEKIVDDLER GDVPLEESIR IYERGEALKK HCDTLLKSAE 70 80 DKVEKIRIGR DGQPVGTEPL DPE

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014291 Genomic DNA. Translation: AAN29374.1. Different initiation.
RefSeq	NP_697459.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1166092.
GenomeReviews	Gene locus BR0431 in contig AE014291_GR.
KEGG	bms:BR0431.
TIGR	BR0431.
Phylogenomic databases
HOGENOM	HBG728416.
Enzyme and pathway databases
BioCyc	BSUI204722:BR_0431-MON.
BRENDA	3.1.11.6. 281610.
Family and domain databases
HAMAP	MF_00337. [Tree]
InterPro	IPR003761. Exonuc_VII_S. [Graphical view]
Pfam	PF02609. Exonuc_VII_S. 1 hit. [Graphical view]
PIRSF	PIRSF006488. Exonuc_VII_S. 1 hit.
ProDom	PD028235. Exonuc_VII_S. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

EX7S_BRUSU

Accession

Primary (citable) accession number: P67455
Secondary accession number(s): Q8YFL7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	December 15, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)