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Protein

UPF0122 protein SPy_1201/M5005_Spy0916

Gene

SPy_1201

Organism
Streptococcus pyogenes serotype M1
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0122 protein SPy_1201/M5005_Spy0916
Gene namesi
Ordered Locus Names:SPy_1201, M5005_Spy0916
OrganismiStreptococcus pyogenes serotype M1
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000750 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002118881 – 113UPF0122 protein SPy_1201/M5005_Spy0916Add BLAST113

Proteomic databases

PaxDbiP67253.
PRIDEiP67253.

Interactioni

Protein-protein interaction databases

STRINGi160490.SPy_1201.

Structurei

Secondary structure

1113
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi10 – 1910
Helixi20 – 223
Helixi25 – 3511
Helixi41 – 488
Helixi52 – 7322
Helixi75 – 9218
Helixi97 – 11014

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1S7OX-ray2.31A/B/C1-113[»]
ProteinModelPortaliP67253.
SMRiP67253.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP67253.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0122 family.Curated

Phylogenomic databases

eggNOGiENOG4105VBN. Bacteria.
COG2739. LUCA.
HOGENOMiHOG000040451.
KOiK09787.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00245. UPF0122. 1 hit.
InterProiView protein in InterPro
IPR013324. RNA_pol_sigma_r3_r4.
IPR007394. UPF0122.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF04297. UPF0122. 1 hit.
SUPFAMiSSF88659. SSF88659. 1 hit.

Sequencei

Sequence statusi: Complete.

P67253-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIMEIEKTN RMNALFEFYA ALLTDKQMNY IELYYADDYS LAEIADEFGV
60 70 80 90 100
SRQAVYDNIK RTEKILETYE MKLHMYSDYV VRSEIFDDMI AHYPHDEYLQ
110
EKISILTSID NRE
Length:113
Mass (Da):13,590
Last modified:October 11, 2004 - v1
Checksum:iD82B0620DDA8873B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK34061.1.
CP000017 Genomic DNA. Translation: AAZ51534.1.
RefSeqiNP_269340.1. NC_002737.2.

Genome annotation databases

EnsemblBacteriaiAAK34061; AAK34061; SPy_1201.
AAZ51534; AAZ51534; M5005_Spy0916.
GeneIDi901306.
KEGGispy:SPy_1201.
spz:M5005_Spy0916.
PATRICifig|160490.10.peg.1048.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiY1201_STRP1
AccessioniPrimary (citable) accession number: P67253
Secondary accession number(s): Q48YN8, Q99ZK0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 7, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries