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Protein

UPF0122 protein SPy_1201/M5005_Spy0916

Gene

SPy_1201

Organism
Streptococcus pyogenes serotype M1
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-993-MONOMER.
SPYO293653:GHFC-975-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0122 protein SPy_1201/M5005_Spy0916
Gene namesi
Ordered Locus Names:SPy_1201, M5005_Spy0916
OrganismiStreptococcus pyogenes serotype M1
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000750 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 113113UPF0122 protein SPy_1201/M5005_Spy0916PRO_0000211888Add
BLAST

Proteomic databases

PaxDbiP67253.

Interactioni

Protein-protein interaction databases

STRINGi160490.SPy_1201.

Structurei

Secondary structure

1
113
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi10 – 1910
Helixi20 – 223
Helixi25 – 3511
Helixi41 – 488
Helixi52 – 7322
Helixi75 – 9218
Helixi97 – 11014

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1S7OX-ray2.31A/B/C1-113[»]
ProteinModelPortaliP67253.
SMRiP67253. Positions 5-112.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP67253.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0122 family.Curated

Phylogenomic databases

eggNOGiENOG4105VBN. Bacteria.
COG2739. LUCA.
HOGENOMiHOG000040451.
KOiK09787.
OMAiKLHMKRD.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00245. UPF0122. 1 hit.
InterProiIPR013324. RNA_pol_sigma_r3_r4.
IPR007394. UPF0122.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04297. UPF0122. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.

Sequencei

Sequence statusi: Complete.

P67253-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIMEIEKTN RMNALFEFYA ALLTDKQMNY IELYYADDYS LAEIADEFGV
60 70 80 90 100
SRQAVYDNIK RTEKILETYE MKLHMYSDYV VRSEIFDDMI AHYPHDEYLQ
110
EKISILTSID NRE
Length:113
Mass (Da):13,590
Last modified:October 11, 2004 - v1
Checksum:iD82B0620DDA8873B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK34061.1.
CP000017 Genomic DNA. Translation: AAZ51534.1.
RefSeqiNP_269340.1. NC_002737.2.

Genome annotation databases

EnsemblBacteriaiAAK34061; AAK34061; SPy_1201.
AAZ51534; AAZ51534; M5005_Spy0916.
GeneIDi901306.
KEGGispy:SPy_1201.
spz:M5005_Spy0916.
PATRICi19715967. VBIStrPyo79812_1048.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK34061.1.
CP000017 Genomic DNA. Translation: AAZ51534.1.
RefSeqiNP_269340.1. NC_002737.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1S7OX-ray2.31A/B/C1-113[»]
ProteinModelPortaliP67253.
SMRiP67253. Positions 5-112.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160490.SPy_1201.

Proteomic databases

PaxDbiP67253.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK34061; AAK34061; SPy_1201.
AAZ51534; AAZ51534; M5005_Spy0916.
GeneIDi901306.
KEGGispy:SPy_1201.
spz:M5005_Spy0916.
PATRICi19715967. VBIStrPyo79812_1048.

Phylogenomic databases

eggNOGiENOG4105VBN. Bacteria.
COG2739. LUCA.
HOGENOMiHOG000040451.
KOiK09787.
OMAiKLHMKRD.

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-993-MONOMER.
SPYO293653:GHFC-975-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP67253.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00245. UPF0122. 1 hit.
InterProiIPR013324. RNA_pol_sigma_r3_r4.
IPR007394. UPF0122.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04297. UPF0122. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiY1201_STRP1
AccessioniPrimary (citable) accession number: P67253
Secondary accession number(s): Q48YN8, Q99ZK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.