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Protein

UPF0073 inner membrane protein YqfA

Gene

yqfA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7512-MONOMER.
ECOL316407:JW2867-MONOMER.
RETL1328306-WGS:GSTH-1237-MONOMER.

Protein family/group databases

TCDBi1.C.113.1.10. 1.c.113 the hly iii (hly iii) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0073 inner membrane protein YqfA
Gene namesi
Name:yqfA
Ordered Locus Names:b2899, JW2867
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13077. yqfA.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2323CytoplasmicSequence analysisAdd
BLAST
Transmembranei24 – 4421HelicalSequence analysisAdd
BLAST
Topological domaini45 – 539PeriplasmicSequence analysis
Transmembranei54 – 7421HelicalSequence analysisAdd
BLAST
Topological domaini75 – 9016CytoplasmicSequence analysisAdd
BLAST
Transmembranei91 – 11121HelicalSequence analysisAdd
BLAST
Topological domaini112 – 1132PeriplasmicSequence analysis
Transmembranei114 – 13421HelicalSequence analysisAdd
BLAST
Topological domaini135 – 1384CytoplasmicSequence analysis
Transmembranei139 – 15921HelicalSequence analysisAdd
BLAST
Topological domaini160 – 1656PeriplasmicSequence analysis
Transmembranei166 – 18621HelicalSequence analysisAdd
BLAST
Topological domaini187 – 1959CytoplasmicSequence analysis
Transmembranei196 – 21621HelicalSequence analysisAdd
BLAST
Topological domaini217 – 2193PeriplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219UPF0073 inner membrane protein YqfAPRO_0000176898Add
BLAST

Proteomic databases

PaxDbiP67153.
PRIDEiP67153.

Interactioni

Protein-protein interaction databases

BioGridi4261705. 8 interactions.
STRINGi511145.b2899.

Structurei

3D structure databases

ProteinModelPortaliP67153.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0073 (Hly-III) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108UT2. Bacteria.
COG1272. LUCA.
HOGENOMiHOG000039438.
InParanoidiP67153.
KOiK11068.
OMAiCINKFEN.
OrthoDBiEOG6QG8NQ.
PhylomeDBiP67153.

Family and domain databases

InterProiIPR004254. AdipoR/HlyIII-related.
IPR005744. Hy-lIII.
[Graphical view]
PANTHERiPTHR20855. PTHR20855. 1 hit.
PTHR20855:SF3. PTHR20855:SF3. 1 hit.
PfamiPF03006. HlyIII. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01065. hlyIII. 1 hit.

Sequencei

Sequence statusi: Complete.

P67153-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQKPLIKQG YSLAEEIANS VSHGIGLVFG IVGLVLLLVQ AVDLNASATA
60 70 80 90 100
ITSYSLYGGS MILLFLASTL YHAIPHQRAK MWLKKFDHCA IYLLIAGTYT
110 120 130 140 150
PFLLVGLDSP LARGLMIVIW SLALLGILFK LTIAHRFKIL SLVTYLAMGW
160 170 180 190 200
LSLVVIYEMA VKLAAGSVTL LAVGGVVYSL GVIFYVCKRI PYNHAIWHGF
210
VLGGSVCHFL AIYLYIGQA
Length:219
Mass (Da):23,847
Last modified:October 11, 2004 - v1
Checksum:iF1D863D2D1A30DA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83080.1.
U00096 Genomic DNA. Translation: AAC75937.1.
AP009048 Genomic DNA. Translation: BAE76964.1.
PIRiC65074.
RefSeqiNP_417375.1. NC_000913.3.
WP_000250274.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75937; AAC75937; b2899.
BAE76964; BAE76964; BAE76964.
GeneIDi947381.
KEGGiecj:JW2867.
eco:b2899.
PATRICi32121212. VBIEscCol129921_2994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83080.1.
U00096 Genomic DNA. Translation: AAC75937.1.
AP009048 Genomic DNA. Translation: BAE76964.1.
PIRiC65074.
RefSeqiNP_417375.1. NC_000913.3.
WP_000250274.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP67153.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261705. 8 interactions.
STRINGi511145.b2899.

Protein family/group databases

TCDBi1.C.113.1.10. 1.c.113 the hly iii (hly iii) family.

Proteomic databases

PaxDbiP67153.
PRIDEiP67153.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75937; AAC75937; b2899.
BAE76964; BAE76964; BAE76964.
GeneIDi947381.
KEGGiecj:JW2867.
eco:b2899.
PATRICi32121212. VBIEscCol129921_2994.

Organism-specific databases

EchoBASEiEB2887.
EcoGeneiEG13077. yqfA.

Phylogenomic databases

eggNOGiENOG4108UT2. Bacteria.
COG1272. LUCA.
HOGENOMiHOG000039438.
InParanoidiP67153.
KOiK11068.
OMAiCINKFEN.
OrthoDBiEOG6QG8NQ.
PhylomeDBiP67153.

Enzyme and pathway databases

BioCyciEcoCyc:G7512-MONOMER.
ECOL316407:JW2867-MONOMER.
RETL1328306-WGS:GSTH-1237-MONOMER.

Miscellaneous databases

PROiP67153.

Family and domain databases

InterProiIPR004254. AdipoR/HlyIII-related.
IPR005744. Hy-lIII.
[Graphical view]
PANTHERiPTHR20855. PTHR20855. 1 hit.
PTHR20855:SF3. PTHR20855:SF3. 1 hit.
PfamiPF03006. HlyIII. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01065. hlyIII. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYQFA_ECOLI
AccessioniPrimary (citable) accession number: P67153
Secondary accession number(s): Q2M9U2, Q46827
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 20, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.