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Protein

UPF0073 inner membrane protein YqfA

Gene

yqfA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7512-MONOMER.
ECOL316407:JW2867-MONOMER.

Protein family/group databases

TCDBi1.C.113.1.10. 1.c.113 the hly iii (hly iii) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0073 inner membrane protein YqfA
Gene namesi
Name:yqfA
Ordered Locus Names:b2899, JW2867
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13077. yqfA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 23CytoplasmicSequence analysisAdd BLAST23
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Topological domaini45 – 53PeriplasmicSequence analysis9
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Topological domaini75 – 90CytoplasmicSequence analysisAdd BLAST16
Transmembranei91 – 111HelicalSequence analysisAdd BLAST21
Topological domaini112 – 113PeriplasmicSequence analysis2
Transmembranei114 – 134HelicalSequence analysisAdd BLAST21
Topological domaini135 – 138CytoplasmicSequence analysis4
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 165PeriplasmicSequence analysis6
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21
Topological domaini187 – 195CytoplasmicSequence analysis9
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Topological domaini217 – 219PeriplasmicSequence analysis3

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001768981 – 219UPF0073 inner membrane protein YqfAAdd BLAST219

Proteomic databases

PaxDbiP67153.
PRIDEiP67153.

Interactioni

Protein-protein interaction databases

BioGridi4261705. 8 interactors.
STRINGi511145.b2899.

Structurei

3D structure databases

ProteinModelPortaliP67153.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0073 (Hly-III) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108UT2. Bacteria.
COG1272. LUCA.
HOGENOMiHOG000039438.
InParanoidiP67153.
KOiK11068.
OMAiASHFWLM.
PhylomeDBiP67153.

Family and domain databases

InterProiIPR004254. AdipoR/HlyIII-related.
IPR005744. Hy-lIII.
[Graphical view]
PANTHERiPTHR20855. PTHR20855. 1 hit.
PTHR20855:SF3. PTHR20855:SF3. 1 hit.
PfamiPF03006. HlyIII. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01065. hlyIII. 1 hit.

Sequencei

Sequence statusi: Complete.

P67153-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQKPLIKQG YSLAEEIANS VSHGIGLVFG IVGLVLLLVQ AVDLNASATA
60 70 80 90 100
ITSYSLYGGS MILLFLASTL YHAIPHQRAK MWLKKFDHCA IYLLIAGTYT
110 120 130 140 150
PFLLVGLDSP LARGLMIVIW SLALLGILFK LTIAHRFKIL SLVTYLAMGW
160 170 180 190 200
LSLVVIYEMA VKLAAGSVTL LAVGGVVYSL GVIFYVCKRI PYNHAIWHGF
210
VLGGSVCHFL AIYLYIGQA
Length:219
Mass (Da):23,847
Last modified:October 11, 2004 - v1
Checksum:iF1D863D2D1A30DA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83080.1.
U00096 Genomic DNA. Translation: AAC75937.1.
AP009048 Genomic DNA. Translation: BAE76964.1.
PIRiC65074.
RefSeqiNP_417375.1. NC_000913.3.
WP_000250274.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75937; AAC75937; b2899.
BAE76964; BAE76964; BAE76964.
GeneIDi947381.
KEGGiecj:JW2867.
eco:b2899.
PATRICi32121212. VBIEscCol129921_2994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83080.1.
U00096 Genomic DNA. Translation: AAC75937.1.
AP009048 Genomic DNA. Translation: BAE76964.1.
PIRiC65074.
RefSeqiNP_417375.1. NC_000913.3.
WP_000250274.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP67153.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261705. 8 interactors.
STRINGi511145.b2899.

Protein family/group databases

TCDBi1.C.113.1.10. 1.c.113 the hly iii (hly iii) family.

Proteomic databases

PaxDbiP67153.
PRIDEiP67153.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75937; AAC75937; b2899.
BAE76964; BAE76964; BAE76964.
GeneIDi947381.
KEGGiecj:JW2867.
eco:b2899.
PATRICi32121212. VBIEscCol129921_2994.

Organism-specific databases

EchoBASEiEB2887.
EcoGeneiEG13077. yqfA.

Phylogenomic databases

eggNOGiENOG4108UT2. Bacteria.
COG1272. LUCA.
HOGENOMiHOG000039438.
InParanoidiP67153.
KOiK11068.
OMAiASHFWLM.
PhylomeDBiP67153.

Enzyme and pathway databases

BioCyciEcoCyc:G7512-MONOMER.
ECOL316407:JW2867-MONOMER.

Miscellaneous databases

PROiP67153.

Family and domain databases

InterProiIPR004254. AdipoR/HlyIII-related.
IPR005744. Hy-lIII.
[Graphical view]
PANTHERiPTHR20855. PTHR20855. 1 hit.
PTHR20855:SF3. PTHR20855:SF3. 1 hit.
PfamiPF03006. HlyIII. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01065. hlyIII. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYQFA_ECOLI
AccessioniPrimary (citable) accession number: P67153
Secondary accession number(s): Q2M9U2, Q46827
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.