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Protein

UPF0056 inner membrane protein YhgN

Gene

yhgN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7753-MONOMER.
ECOL316407:JW3397-MONOMER.

Protein family/group databases

TCDBi2.A.95.1.5. the 6tms neutral amino acid transporter (naat) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0056 inner membrane protein YhgN
Gene namesi
Name:yhgN
Ordered Locus Names:b3434, JW3397
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12941. yhgN.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3PeriplasmicSequence analysis3
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Topological domaini25 – 44CytoplasmicSequence analysisAdd BLAST20
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Topological domaini66 – 71PeriplasmicSequence analysis6
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Topological domaini93 – 105CytoplasmicSequence analysisAdd BLAST13
Transmembranei106 – 126HelicalSequence analysisAdd BLAST21
Topological domaini127 – 138PeriplasmicSequence analysisAdd BLAST12
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 173CytoplasmicSequence analysisAdd BLAST14
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Topological domaini195 – 197PeriplasmicSequence analysis3

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001569021 – 197UPF0056 inner membrane protein YhgNAdd BLAST197

Proteomic databases

PaxDbiP67143.
PRIDEiP67143.

Interactioni

Protein-protein interaction databases

BioGridi4259298. 183 interactors.
STRINGi511145.b3434.

Structurei

3D structure databases

ProteinModelPortaliP67143.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0056 (MarC) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41076UM. Bacteria.
COG2095. LUCA.
HOGENOMiHOG000112970.
InParanoidiP67143.
OMAiIRMIFPQ.
PhylomeDBiP67143.

Family and domain databases

InterProiIPR002771. Multi_antbiot-R_MarC.
[Graphical view]
PfamiPF01914. MarC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00427. TIGR00427. 1 hit.

Sequencei

Sequence statusi: Complete.

P67143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEIISAAVL LILIMDPLGN LPIFMSVLKH TEPKRRRAIM VRELLIALLV
60 70 80 90 100
MLVFLFAGEK ILAFLSLRAE TVSISGGIIL FLIAIKMIFP SASGNSSGLP
110 120 130 140 150
AGEEPFIVPL AIPLVAGPTI LATLMLLSHQ YPNQMGHLVI ALLLAWGGTF
160 170 180 190
VILLQSSLFL RLLGEKGVNA LERLMGLILV MMATQMFLDG IRMWMKG
Length:197
Mass (Da):21,490
Last modified:October 11, 2004 - v1
Checksum:iC3A2B0223545B212
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58232.1.
U00096 Genomic DNA. Translation: AAC76459.1.
AP009048 Genomic DNA. Translation: BAE77858.1.
PIRiE65139.
RefSeqiNP_417892.1. NC_000913.3.
WP_001002544.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76459; AAC76459; b3434.
BAE77858; BAE77858; BAE77858.
GeneIDi947938.
KEGGiecj:JW3397.
eco:b3434.
PATRICi32122308. VBIEscCol129921_3531.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58232.1.
U00096 Genomic DNA. Translation: AAC76459.1.
AP009048 Genomic DNA. Translation: BAE77858.1.
PIRiE65139.
RefSeqiNP_417892.1. NC_000913.3.
WP_001002544.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP67143.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259298. 183 interactors.
STRINGi511145.b3434.

Protein family/group databases

TCDBi2.A.95.1.5. the 6tms neutral amino acid transporter (naat) family.

Proteomic databases

PaxDbiP67143.
PRIDEiP67143.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76459; AAC76459; b3434.
BAE77858; BAE77858; BAE77858.
GeneIDi947938.
KEGGiecj:JW3397.
eco:b3434.
PATRICi32122308. VBIEscCol129921_3531.

Organism-specific databases

EchoBASEiEB2776.
EcoGeneiEG12941. yhgN.

Phylogenomic databases

eggNOGiENOG41076UM. Bacteria.
COG2095. LUCA.
HOGENOMiHOG000112970.
InParanoidiP67143.
OMAiIRMIFPQ.
PhylomeDBiP67143.

Enzyme and pathway databases

BioCyciEcoCyc:G7753-MONOMER.
ECOL316407:JW3397-MONOMER.

Miscellaneous databases

PROiP67143.

Family and domain databases

InterProiIPR002771. Multi_antbiot-R_MarC.
[Graphical view]
PfamiPF01914. MarC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00427. TIGR00427. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYHGN_ECOLI
AccessioniPrimary (citable) accession number: P67143
Secondary accession number(s): P46851, Q2M798
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.