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Protein

UPF0053 inner membrane protein YgdQ

Gene

ygdQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7460-MONOMER.
ECOL316407:JW2800-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0053 inner membrane protein YgdQ
Gene namesi
Name:ygdQ
Ordered Locus Names:b2832, JW2800
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13092. ygdQ.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1717PeriplasmicSequence analysisAdd
BLAST
Transmembranei18 – 3821HelicalSequence analysisAdd
BLAST
Topological domaini39 – 5012CytoplasmicSequence analysisAdd
BLAST
Transmembranei51 – 7121HelicalSequence analysisAdd
BLAST
Topological domaini72 – 798PeriplasmicSequence analysis
Transmembranei80 – 10021HelicalSequence analysisAdd
BLAST
Topological domaini101 – 12424CytoplasmicSequence analysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence analysisAdd
BLAST
Topological domaini146 – 1516PeriplasmicSequence analysis
Transmembranei152 – 17221HelicalSequence analysisAdd
BLAST
Topological domaini173 – 18614CytoplasmicSequence analysisAdd
BLAST
Transmembranei187 – 20721HelicalSequence analysisAdd
BLAST
Topological domaini208 – 2092PeriplasmicSequence analysis
Transmembranei210 – 23021HelicalSequence analysisAdd
BLAST
Topological domaini231 – 2377CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237UPF0053 inner membrane protein YgdQPRO_0000088366Add
BLAST

Proteomic databases

PaxDbiP67127.
PRIDEiP67127.

Interactioni

Protein-protein interaction databases

BioGridi4263142. 12 interactions.
STRINGi511145.b2832.

Structurei

3D structure databases

ProteinModelPortaliP67127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0053 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EE5. Bacteria.
COG0861. LUCA.
HOGENOMiHOG000258483.
InParanoidiP67127.
OMAiVHSFFGA.
OrthoDBiEOG6F297P.
PhylomeDBiP67127.

Family and domain databases

InterProiIPR005496. Integral_membrane_TerC.
[Graphical view]
PfamiPF03741. TerC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P67127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFAWITDPN AWLALGTLTL LEIVLGIDNI IFLSLVVAKL PTAQRAHARR
60 70 80 90 100
LGLAGAMVMR LALLASIAWV TRLTNPLFTI FSQEISARDL ILLLGGLFLI
110 120 130 140 150
WKASKEIHES IEGEEEGLKT RVSSFLGAIV QIMLLDIIFS LDSVITAVGL
160 170 180 190 200
SDHLFIMMAA VVIAVGVMMF AARSIGDFVE RHPSVKMLAL SFLILVGFTL
210 220 230
ILESFDIHVP KGYIYFAMFF SIAVESLNLI RNKKNPL
Length:237
Mass (Da):26,157
Last modified:October 11, 2004 - v1
Checksum:iE5680AB2054A0D8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29581 Genomic DNA. Translation: AAB40479.1.
U00096 Genomic DNA. Translation: AAC75871.1.
AP009048 Genomic DNA. Translation: BAE76901.1.
PIRiA65066.
RefSeqiNP_417309.1. NC_000913.3.
WP_000895624.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75871; AAC75871; b2832.
BAE76901; BAE76901; BAE76901.
GeneIDi947295.
KEGGiecj:JW2800.
eco:b2832.
PATRICi32121082. VBIEscCol129921_2930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29581 Genomic DNA. Translation: AAB40479.1.
U00096 Genomic DNA. Translation: AAC75871.1.
AP009048 Genomic DNA. Translation: BAE76901.1.
PIRiA65066.
RefSeqiNP_417309.1. NC_000913.3.
WP_000895624.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP67127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263142. 12 interactions.
STRINGi511145.b2832.

Proteomic databases

PaxDbiP67127.
PRIDEiP67127.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75871; AAC75871; b2832.
BAE76901; BAE76901; BAE76901.
GeneIDi947295.
KEGGiecj:JW2800.
eco:b2832.
PATRICi32121082. VBIEscCol129921_2930.

Organism-specific databases

EchoBASEiEB2897.
EcoGeneiEG13092. ygdQ.

Phylogenomic databases

eggNOGiENOG4105EE5. Bacteria.
COG0861. LUCA.
HOGENOMiHOG000258483.
InParanoidiP67127.
OMAiVHSFFGA.
OrthoDBiEOG6F297P.
PhylomeDBiP67127.

Enzyme and pathway databases

BioCyciEcoCyc:G7460-MONOMER.
ECOL316407:JW2800-MONOMER.

Miscellaneous databases

PROiP67127.

Family and domain databases

InterProiIPR005496. Integral_membrane_TerC.
[Graphical view]
PfamiPF03741. TerC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYGDQ_ECOLI
AccessioniPrimary (citable) accession number: P67127
Secondary accession number(s): Q2MA05, Q46931
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 20, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.