P67126 (Y1496_MYCBO) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 46.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: UPF0051 protein Mb1496 Cleaved into the following chain:
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| Gene names |
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| Organism | Mycobacterium bovis [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 1765 [NCBI] | ||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex |
Protein attributes
| Sequence length | 846 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Post-translational modification | This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation Potential. |
| Sequence similarities | Belongs to the UPF0051 (ycf24) family. Contains 1 DOD-type homing endonuclease domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Intron homing |
| Molecular function | Endonuclease Hydrolase Nuclease |
| PTM | Autocatalytic cleavage Protein splicing |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | intein-mediated protein splicing Inferred from electronic annotation. Source: InterPro intron homingInferred from electronic annotation. Source: UniProtKB-KW iron-sulfur cluster assemblyInferred from electronic annotation. Source: InterPro |
| Molecular function | endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 252 | 252 | UPF0051 protein Mb1496, 1st part Potential | PRO_0000036193 | |||||
| Chain | 253 – 611 | 359 | Endonuclease PI-MtuHIIP Potential | PRO_0000036194 | |||||
| Chain | 612 – 846 | 235 | UPF0051 protein Mb1496, 2nd part Potential | PRO_0000036195 | |||||
Regions | |||||||||
| Domain | 388 – 528 | 141 | DOD-type homing endonuclease | ||||||
Sequences
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References
| [1] | "The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. Hewinson R.G.Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX248339 Genomic DNA. Translation: CAD96163.1. |
| RefSeq | NP_855148.1. NC_002945.3. |
3D structure databases | |
| ProteinModelPortal | P67126. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBMYCT00000016617; EBMYCP00000016452; EBMYCG00000016612. |
| GeneID | 1092353. |
| GenomeReviews | Gene locus Mb1496 in contig BX248333_GR. |
| KEGG | mbo:Mb1496. |
| PATRIC | 18004980. VBIMycBov88188_1637. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000017319. |
| HOGENOM | HBG130984. |
| ProtClustDB | CLSK791176. |
Enzyme and pathway databases | |
| BioCyc | MBOV233413:MB1496-MONOMER. |
Family and domain databases | |
| InterPro | IPR003586. Hedgehog_hint_C. IPR003587. Hedgehog_hint_N. IPR007868. Hom_end_hint. IPR006142. INTEIN. IPR004042. Intein_endonuc. IPR006141. Intein_splice_site. IPR010231. SUF_FeS_clus_asmbl_SufB. IPR000825. SUF_FeS_clus_asmbl_SufBD. [Graphical view] |
| KO | K09014. |
| Pfam | PF05203. Hom_end_hint. 1 hit. PF01458. UPF0051. 1 hit. [Graphical view] |
| PRINTS | PR00379. INTEIN. |
| SMART | SM00305. HintC. 1 hit. SM00306. HintN. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01443. Intein_Cterm. 1 hit. TIGR01980. SufB. 1 hit. |
| PROSITE | PS50818. INTEIN_C_TER. 1 hit. PS50819. INTEIN_ENDONUCLEASE. 1 hit. PS50817. INTEIN_N_TER. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Y1496_MYCBO | ||||||||
| Accession | Primary (citable) accession number: P67126 Secondary accession number(s): O53152 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Intein-containing proteins List of intein-containing protein entries |
| Uncharacterized protein families (UPF) List of uncharacterized protein family (UPF) entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with